Results 31 to 40 of about 16,411 (186)

Optimizing Parathyroid Localization in Real Life: The Role of Expert‐Performed Ultrasonography

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To evaluate the accuracy of expert‐performed ultrasonography (US) for preoperative localization in minimally invasive parathyroidectomy (MIP) compared with community US and other imaging modalities. Study Design Retrospective cohort study. Setting Tertiary referral center for endocrine surgery.
Tzahi Yamin, Nir Battat, Annat Blank, Shmuel Meirsdorf, Bar Sara Zigdon, Oded Cohen, Avi Khafif   +6 more
wiley   +1 more source

Malignancy in Pediatric Hyperfunctioning Thyroid Nodules: A Case Report and Literature Review

Clinical Endocrinology, EarlyView.
ABSTRACT Background Thyroid nodules are rare in children but carry a markedly higher risk of malignancy compared to adults (20%–26% vs. 5%). Hyperfunctioning thyroid nodules are exceptionally uncommon in the pediatric population and are typically benign.
Cristina Clausi, Simona Censi, Jacopo Maria Arnone, Giulia Messina, Ilaria Piva, Fausto Cortese, Loris Bertazza, Susi Barollo, Francesca Galuppini, Marco Zarantonello, Maurizio Iacobone, Gianmaria Pennelli, Caterina Mian   +12 more
wiley   +1 more source

Diagnostic Options in Graves' or Non‐Graves' Thyrotoxicosis: A Review for Clinical Practice

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Distinguishing Graves' disease (GD) from the other causes of thyrotoxicosis is essential for appropriate management. The clinical phenotype of GD has evolved over time and is currently more heterogenous and milder than in the past. Consequently, the differential diagnosis of thyrotoxicosis is often challenging.
Lorenzo Scappaticcio, Pierpaolo Trimboli, Paola Caruso, Chiara Porcellini, Daniela Forestiere, Maria Ida Maiorino, Katherine Esposito, Giuseppe Bellastella   +7 more
wiley   +1 more source

Synthesis and Evaluation of Novel Norfloxacin Isonitrile ^99mTc Complexes as Potential Bacterial Infection Imaging Agents

Pharmaceutics, 2021
To develop potential technetium-99m single-photon emission computed tomography (SPECT) imaging agents for bacterial infection imaging, the novel norfloxacin isonitrile derivatives CN4NF and CN5NF were synthesized and radiolabeled with a [99mTc][Tc(I ...
Si’an Fang, Yuhao Jiang, Di Xiao, Xuran Zhang, Qianqian Gan, Qing Ruan, Junbo Zhang   +6 more
doaj   +1 more source

Two Contrasting Scintigraphy‐Negative Pediatric Meckel's Diverticula Identified and Localized by Intestinal Ultrasound and Double‐Balloon Enteroscopy: A Report of Two Cases

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Scintigraphy‐negative Meckel's diverticulum (MD) is diagnostically challenging in children, particularly when the underlying pathology differs between cases. Technetium‐99m pertechnetate scintigraphy is widely used for diagnosis; however, false‐negative results may occur when ectopic gastric mucosa is absent or when the diverticulum is ...
Saki Kasai, Masumi Nagata, Keisuke Jimbo, Nobuyasu Arai, Yuichiro Miyake, Mitsuyoshi Suzuki, Takahiro Kudo, Go Miyano, Hiromichi Shoji   +8 more
wiley   +1 more source

Characteristics and long‐term outcomes of children with confirmed focal cortical dysplasia type 1 after epilepsy surgery: A population‐based study

Epilepsia Open, Volume 11, Issue 4, Page 1314-1328, August 2026.
Abstract Objective Focal cortical dysplasia type 1 (FCD1) is a rare and heterogeneous cause of drug‐resistant epilepsy (DRE) in children. Its clinical characteristics remain poorly understood, and surgical outcomes may be less favorable than in FCD2. We conducted a population‐based study to characterize the clinical presentation and long‐term seizure ...
Vincent Zheng, Päivi Koroknay‐Pál, Henri Lehtinen, Eija Gaily, Atte Karppinen, Anders Paetau, Olli Tynninen, Heta Leinonen, Aki Laakso, Eeva‐Liisa Metsähonkala   +9 more
wiley   +1 more source

Heroin Vapor Inhalation-induced Spongiform Leukoencephalopathy

Journal of the Formosan Medical Association, 2009
A 26-year-old man with a 3-year history of heroin vapor inhalation developed spongiform leukoencephalopathy. T2-weighted magnetic resonance imaging showed characteristic high signals over subcortical white matter, including bilateral frontoparietal lobes,
Rou-Chen Jee, Wen-Lung Tsao, Woei-Cherng Shyu, Pao-Sheng Yen, Yung-Hsiang Hsu, Shu-Hsin Liu   +5 more
doaj   +1 more source

Design, Preparation, and Evaluation of a Novel ^99mTcN Complex of Ciprofloxacin Xanthate as a Potential Bacterial Infection Imaging Agent

Molecules, 2020
In order to seek novel technetium-99m bacterial infection imaging agents, a ciprofloxacin xanthate (CPF2XT) was synthesized and radiolabeled with [99mTcN]2+ core to obtain the 99mTcN-CPF2XT complex, which exhibited high radiochemical purity ...
Si’an Fang, Yuhao Jiang, Qianqian Gan, Qing Ruan, Di Xiao, Junbo Zhang   +5 more
doaj   +1 more source

Phosphorescent Iridium Hydrazinonicotinic Acid (HYNIC) Complexes That Bind to Prostate Specific Membrane Antigen: Potential Photodynamic Therapy of Prostate Cancer

Chemistry – A European Journal, Volume 32, Issue 25, 2 July 2026.
A phosphorescent iridium(III) complex has been prepared with a 6‐hydrazinonicotinic acid (HYNIC) ligand tethered to a lysine‐ureido‐glutamatic acid pharmacophore, which binds to an enzyme, called prostate‐specific membrane antigen (PSMA), which is overexpressed in prostate cancer.
La'El Kimchi, Emily R. McGowan, Katherine A. Morgan, Jonathan M. White, Trevor A. Smith, Stacey E. Rudd, Paul S. Donnelly   +6 more
wiley   +1 more source

Use of Technetium‐99m‐Pyrophosphate Single‐Photon Emission Computed Tomography/Computed Tomography in Monitoring Therapeutic Changes of Eplontersen in Patients With Hereditary Transthyretin Amyloid Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Hereditary transthyretin amyloid cardiomyopathy (hATTR‐CM) is a progressive and fatal disease. Recent evidence indicates that bone scintigraphy may serve as a tool to monitor the effectiveness of hATTR‐CM treatment. The objective of this study
An‐Li Yu, Yi‐Chieh Chen, Cheng‐Hsuan Tsai, Yuan‐Kun Aden Wu, Mao‐Yuan Su, Chia‐Hung Chou, Chia‐Tung Shun, Hsueh‐Wen Hsueh, Jimmy Jyh‐Ming Juang, Ming‐Jen Lee, Ping‐Huei Tseng, Chia‐Hua Hsu, Sung‐Tsang Hsieh, Chi‐Lun Ko, Mei‐Fang Cheng, Chi‐Chao Chao, Yen‐Hung Lin   +16 more
doaj   +1 more source