Results 11 to 20 of about 30,877 (233)

Effect of an extract of Centella asiatica on the biodistribution of sodium pertechnetate (Na^99mTcO₄) and on the fixation of radioactivity on blood constituents [PDF]

, 2008
This study evaluates the effects of an acute treatment with a Centella asiatica (CA) extract on the biodistribution of the radiopharmaceutical Na99mTcO4 and on the fixation of technetium-99m on blood constituents. Wistar rats were treated with CA extract
Adenilson de Souza da Fonseca, Benarroz M. O., Bernardo-Filho M., Capriles P. V., Claudia Leite Diniz, Danielle Santos de Almeida, Fernanda Santos do Carmo, Fonseca A. S., Frydman J. N. G., Goel H. C., Inamdar P. K., Jayashree G., Mario Bernardo Filho, Moreno S.R., Owunwanne A., Padma P. R., Rebello B. M., Saha G. B., Sebastião David Santos-Filho, Sharma J., Shobi V., Simões C. M. O., Sotiris Missailidis   +22 more
core   +4 more sources

A Picture of Modern Tc-99m Radiopharmaceuticals: Production, Chemistry, and Applications in Molecular Imaging

Applied Sciences, 2019
Even today, techentium-99m represents the radionuclide of choice for diagnostic radio-imaging applications. Its peculiar physical and chemical properties make it particularly suitable for medical imaging.
Alessandra Boschi, Licia Uccelli, Petra Martini   +2 more
doaj   +1 more source

Breast cancer: Monitoring response to neoadjuvant chemotherapy using Tc-99m sestamibi scintimammography [PDF]

, 2003
Background: Aim of the study was to assess the value of scintimammography using Tc-99m sestamibi in the evaluation of tumor response to neoadjuvant chemotherapy.
Brinkbäumer, K., Hahn, K., Keßler, M., Linke, R., Sommer, H., Tiling, R., Untch, M.   +6 more
core   +1 more source

Technetium Complexes and Radiopharmaceuticals with Scorpionate Ligands

Molecules, 2018
Scorpionate ligands have played a crucial role in the development of technetium chemistry and, recently, they have also fueled important advancements in the discovery of novel diagnostic imaging agents based on the γ-emitting radionuclide ...
Petra Martini, Micol Pasquali, Alessandra Boschi, Licia Uccelli, Melchiore Giganti, Adriano Duatti   +5 more
doaj   +1 more source

The role of gated myocardial perfusion scintigraphy (GMPS) in myocarditis: A case report and review of the literature [PDF]

, 2011
Acute myocarditis is one of the most challenging diagnoses and treatments in cardiology. The acute viral myocarditis diagnosis is usually based on high suspicion, history taking, and physical examination.
Amini, A., Assadi, M., Jallalat, S., Javadi, H., Mogharrabi, M., Nabipour, I., Pourbehi, G., Ravanbod, M., Semnani, S.   +8 more
core   +2 more sources

The optimization method for synthesis of technetium-99m-luteolin as radiotracer in the development of cancer drugs from flavonoid

Journal of Advanced Pharmaceutical Technology & Research, 2020
The aim of this study is to find the optimum conditions of labeling luteolin flavonoid compounds with technetium-99m (99mTc) to meet the purity requirements stated in the United States Pharmacopeia. This compound is expected to be a potential radiotracer
Danni Ramdhani, Maula Eka Sriyani, S Fairuz Nabila   +2 more
doaj   +1 more source

Synthesis and Evaluation of ^99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

Pharmaceuticals, 2023
When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms.
Qing Ruan, Yitong Liu, Lihao Liao, Jinyu Hao, Yuhao Jiang, Jianyong Jiang, Junbo Zhang   +6 more
doaj   +1 more source

Influence of Storage Temperature on Radiochemical Purity of 99mTc-Radiopharmaceuticals [PDF]

, 2018
The influence of effective room temperature on the radiochemical purity of 99mTc-radiopharmaceuticals was reported. This study was born from the observation that in the isolators used for the preparation of the 99mTc-radiopharmaceuticals the ...
Bartolomei, Mirco, Boschi, Alessandra, Cittanti, Corrado, Donatella, Farina, Doretta, Bortolotti, Elena, Govoni, Elisa, Zappaterra, Giganti, Melchiore, Luca, Lodi, Martini, Petra, Rizzo, Carlotta, Samanta, Zaccaria, Simona, Romani, Stefania, Bertelli, Uccelli, Licia   +14 more
core   +2 more sources

Comparison of the absorbed dose for 99m Tc-diethylenetriaminepentaacetic acid and 99m Tc-ethylenedicysteine radiopharmaceuticals using medical internal radiation dosimetry

Journal of Medical Signals and Sensors, 2015
The aim of this study was the investigation of absorbed dose to the kidneys, spleen, and liver during technetium-99 m ethylene dicysteine and technetium-99 m diethylenetriaminepentaacetic acid ( 99m Tc-EC and 99m Tc-DTPA) kidney scan.
Shokufeh Pirdamooie, Ahmad Shanei, Masoud Moslehi   +2 more
doaj   +1 more source

Synthesis, metal complexation and biological evaluation of a novel semi-rigid bifunctional chelating agent for 99mTc labelling [PDF]

, 2006
A novel bifunctional chelating agent bearing an aromatic ring has been synthesised and characterised. This ligand formed well-defined oxorhenium complexes.
Benoist, Eric, Coulais, Yvon, Gressier, Marie, Le Gal, Julien, Michaud, Sandra   +4 more
core   +2 more sources