Results 11 to 20 of about 40,279 (216)

Radiolabeling of cidofovir with technetium-99m and biodistribution studies [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2020
Radiolabeling cidofovir with technetium-99m (99mTc-CDV) is an innovative procedure that enables real-time monitoring of the drug. Essays were performed in vitro, showing high radiolabel stability within 24 h. Blood clearance, biodistribution studies, and
Raquel Gregorio Arribada, Nara Caroline Pereira, Valbert Nascimento Cardoso, Armando da Silva Cunha Júnior, André Luís Branco de Barros   +4 more
doaj   +2 more sources

Technetium-99m nitrido radiopharmaceuticals with unprecedented biological properties [PDF]

Brazilian Archives of Biology and Technology, 2002
The chemical methods for the production of technetium-99m radiopharmaceuticals containing a terminal TcºN triple bond have been established more than a decade ago.
Adriano Duatti, Alessandra Boschi, Licia Uccelli   +2 more
doaj   +2 more sources

Chelator Free Radiolabeling and Preclinical Evaluation of η⁶-Arene Sandwich Complexes of Lenalidomide With Rhenium and Technetium-99m. [PDF]

Chembiochem
Direct, chelator‐free radiolabeling of lenalidomide is achieved via η6‐arene coordination to technetium‐99m and rhenium, forming sandwich complexes. The radiotracer shows rapid blood clearance, predominant renal excretion, and good in vivo stability, highlighting its potential as a pharmacokinetic probe.
Nadeem Q, Battistin F, Valdés DH, Genady AR, Mendez LRS, Sadeghi S, Blacque O, Alberto R.   +7 more
europepmc   +2 more sources

TECHNETIUM-99M SULFUR COLLOID LABELLED LEUKOCYTES: LABELLING METHOD, DISTRIBUTION, AND SCINTIGRAPHIC DETECTION OF INFLAMMATORY PROCESSES.

, 1975
TECHNETIUM-99M SULFUR COLLOID LABELLED LEUKOCYTES: LABELLING METHOD, DISTRIBUTION, AND SCINTIGRAPHIC DETECTION OF INFLAMMATORY ...
DENIS KELVIN. ENGLISH (7989617)
core   +6 more sources

Assessing Correlation of Quantitative Technetium-99m Sestamibi Uptake in Thyroid Scintigraphy With Treatment Duration in Amiodarone-Induced Thyrotoxicosis. [PDF]

J Med Imaging Radiat Oncol
Journal of Medical Imaging and Radiation Oncology, Volume 70, Issue 5, Page 438-439, August 2026.
Wang R, Better N, Sivaratnam D, Westcott J, Forehan S, Pattison DA, Fourlanos S.   +6 more
europepmc   +2 more sources

Breast cancer: Monitoring response to neoadjuvant chemotherapy using Tc-99m sestamibi scintimammography [PDF]

, 2003
Background: Aim of the study was to assess the value of scintimammography using Tc-99m sestamibi in the evaluation of tumor response to neoadjuvant chemotherapy.
Sommer, H., Keßler, M., Tiling, R., Brinkbäumer, K., Hahn, K., Untch, M., Linke, R.   +6 more
core   +1 more source

The optimization method for synthesis of technetium-99m-luteolin as radiotracer in the development of cancer drugs from flavonoid

Journal of Advanced Pharmaceutical Technology & Research, 2020
The aim of this study is to find the optimum conditions of labeling luteolin flavonoid compounds with technetium-99m (99mTc) to meet the purity requirements stated in the United States Pharmacopeia. This compound is expected to be a potential radiotracer
Danni Ramdhani, Maula Eka Sriyani, S Fairuz Nabila   +2 more
doaj   +1 more source

Synthesis and Evaluation of ^99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

Pharmaceuticals, 2023
When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms.
Qing Ruan, Yitong Liu, Lihao Liao, Jinyu Hao, Yuhao Jiang, Jianyong Jiang, Junbo Zhang   +6 more
doaj   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

Determining Split Renal Function in Children With Ureteropelvic Junction Stenosis: Technetium-99m Mercaptoacetyltriglycine (Tc-99m MAG-3) or Technetium-99m Dimercaptosuccinic Acid (Tc-99m DMSA)? [PDF]

Cureus
Background Ureteropelvic junction stenosis (UPJS) is the most common cause of clinically significant antenatal hydronephrosis. We compared separate renal function results obtained using technetium-99mmercaptoacetyltriglycine (Tc-99m MAG-3) and technetium-
Özdemir H, Girişgen İ, Yaylalı O, Becerir T, Herek Ö, Şenol H, Yüksel S.   +6 more
europepmc   +2 more sources