Results 1 to 10 of about 16,411 (186)

Technetium-99m in production and use [PDF]

Nuclear Technology and Radiation Protection, 2009
Several types of generators have been developed for the production of 99mTc. Due to its excellent performances, the chromatographic type, based on the fission-produced 99Mo sorbed in alumina, is predominant.
Vučina Jurij, Nikolić Nadežda, Petrović Đokica   +2 more
doaj   +3 more sources

A Mathematical Model for Production and Inventory Management of Time-sensitive Pharmaceutical in a Molecular Imaging Center [PDF]

تصمیم گیری و تحقیق در عملیات, 2021
Purpose: The chemical attributes of Technetium-99m have made it popular for most medical imaging procedures. However, in recent years, the decay product of molybdenum-99, i.e., technetium-99m, has become expensive, and its routine availability can no ...
Mohammad Namakshenas, Mohammad Mahdavi Mazdeh   +1 more
doaj   +1 more source

Exploratory Study of the Clinical Value of Near-Infrared Sentinel Lymph Node Mapping With Indocyanine Green in Vulvar Cancer Patients

Frontiers in Oncology, 2021
BackgroundThis study aimed to evaluate the clinical value of indocyanine green sentinel lymph node (SLN) mapping in patients with vulvar cancer. The conventional procedure of SLN mapping in vulvar cancer includes peritumoral injection of technetium-99m ...
Franziska Siegenthaler, Sara Imboden, Laura Knabben, Stefan Mohr, Andrea Papadia, Michael D. Mueller   +5 more
doaj   +1 more source

Technetium-99m-MIBI-SPECT for prostate cancer diagnosis

Український Журнал Нефрології та Діалізу, 2020
The gold standard method for prostate cancer diagnosis is a transrectal ultrasonography-guided prostate biopsy. The detection rate of prostate cancer using the biopsy is approximately 25-30%.
M. Kuru, Z. Talat, M. S. Sağer, Ç. Demirdağ   +3 more
doaj   +1 more source

Lymphoscintigraphy Using Tilmanocept Detects Multiple Sentinel Lymph Nodes in Melanoma Patients

Cancer Control, 2023
Background Technetium-99m-labeled Tilmanocept, a multivalent mannose, is readily internalized by the CD206 surface receptor on macrophages and dendritic cells which are abundantly present in lymph nodes.
Daniel M. Balkin MD, PhD, Gregory J. Tranah PhD, Frederick Wang MD, Cristina O’Donoghue MD, MPH, Emily A. Morell MD, Caitlin Porubsky DO, Mehdi Nosrati MS, Edith M. Vaquero BA, HanKyul Kim BA, Michael J. Carr MD, Jaime L. Montilla-Soler MD, Max C. Wu MD, Donald M. Torre CNMT, Mohammed Kashani-Sabet MD, Jonathan S. Zager MD, FACS, Stanley P. Leong MD, MS, FACS   +15 more
doaj   +1 more source

Physicochemical and Biological Study of ^99mTc and ⁶⁸Ga Radiolabelled Ciprofloxacin and Evaluation of [^99mTc]Tc-CIP as Potential Diagnostic Radiopharmaceutical for Diabetic Foot Syndrome Imaging

Tomography, 2021
This paper presents the application of ciprofloxacin as a biologically active molecule (vector) for delivering diagnostic radiopharmaceuticals to the sites of bacterial infection.
Przemysław Koźmiński, Weronika Gawęda, Magdalena Rzewuska, Agata Kopatys, Szymon Kujda, Marta K. Dudek, Paweł Krzysztof Halik, Leszek Królicki, Ewa Gniazdowska   +8 more
doaj   +1 more source

Technetium Tc 99m tilmanocept fails to detect sentinel lymph nodes in endometrial cancer

Gynecologic Oncology Reports, 2022
Background: Technetium Tc 99m tilmanocept is a synthetic radiotracer specifically designed for sentinel lymph node (SLN) mapping that has been FDA-approved in breast cancer, melanoma, and head and neck cancer.
Ravali A. Reddy, Ashley S. Moon, Stephanie Chow, Lucas Heilbroner, Brooke Howitt, Elisabeth Diver, Oliver Dorigo, Babak Litkouhi, Malte Renz, Amer Karam   +9 more
doaj   +1 more source

Preparation and Bioevaluation of Novel ^99mTc-Labeled Complexes with a 2-Nitroimidazole HYNIC Derivative for Imaging Tumor Hypoxia

Pharmaceuticals, 2021
To develop novel 99mTc-labeled single-photon emission computed tomography (SPECT) radiotracers for imaging hypoxia, a novel HYNICNM ligand (6-hydrazinonicotinamide (HYNIC) 2-nitroimidazole derivative) was designed and synthesized.
Qing Ruan, Qianqian Gan, Xuran Zhang, Si’an Fang, Junbo Zhang   +4 more
doaj   +1 more source

A Picture of Modern Tc-99m Radiopharmaceuticals: Production, Chemistry, and Applications in Molecular Imaging

Applied Sciences, 2019
Even today, techentium-99m represents the radionuclide of choice for diagnostic radio-imaging applications. Its peculiar physical and chemical properties make it particularly suitable for medical imaging.
Alessandra Boschi, Licia Uccelli, Petra Martini   +2 more
doaj   +1 more source

Technetium Complexes and Radiopharmaceuticals with Scorpionate Ligands

Molecules, 2018
Scorpionate ligands have played a crucial role in the development of technetium chemistry and, recently, they have also fueled important advancements in the discovery of novel diagnostic imaging agents based on the γ-emitting radionuclide ...
Petra Martini, Micol Pasquali, Alessandra Boschi, Licia Uccelli, Melchiore Giganti, Adriano Duatti   +5 more
doaj   +1 more source