Results 51 to 60 of about 16,411 (186)

Synthesis and Evaluation of 99mTc Essential Analogue of DUPA PSMA Inhibitor for Its Potential Use in Prostate Cancer Imaging

ChemistrySelect, Volume 11, Issue 21, 4 June 2026.
ABSTRACT DUPA (2‐[3‐(1,3‐dicarboxy propyl) ureido] pentanedioic acid) is a known small molecule prostate‐specific membrane antigen (PSMA) enzyme inhibitor that targets the PSMA receptor found overexpressed on prostate cancer. The present work synthesizes and evaluates a 99mTc (technetium) “metal essential” glutamate complex, which mimics the DUPA ...
Navin Sakhare, Sheela Muralidharan, Dheeraj Kumar, Shubhankar Dutta, Rani Gnanasekar, Shalaka Paradkar, Arpit Mitra, Bhabani Mohanty, Shubhangi Mirapurkar, Anupam Mathur, Pradip R. Chaudhari, Kakoli Bose   +11 more
wiley   +1 more source

Synthesis and Biological Evaluation of Novel Mixed-Ligand ^99mTc-Labeled Anthraquinone Complexes as Potential DNA-Targeted Imaging Agents

Inorganics
Anthraquinones are molecules with numerous biological properties that can act as DNA intercalators and topoisomerase IIa inhibitors. In this work, the development of technetium-99m radiotracers was pursued via the technetium-tricarbonyl “2 + 1” mixed ...
Theofanis Matthaios Migkos, Pigi Glykofridi, Georgios Paparidis, George Psomas, Ioannis S. Vizirianakis, Catherine Gabriel, Dimosthenis Sarigiannis, Ioannis Iakovou, Dionysia Papagiannopoulou   +8 more
doaj   +1 more source

Biochemical bone biomarkers in plasma cell dyscrasias

British Journal of Haematology, Volume 208, Issue 6, Page 1909-1923, June 2026.
Visual abstract depicting that bone turnover markers reflect dynamic alterations in bone remodelling across the spectrum of plasma cell dyscrasias but remain limited by assay variability, biological confounding and incomplete integration with imaging and risk stratification.
Guido Nador, Rohit Vijjhalwar, Muhammad Kassim Javaid, Claire M. Edwards, Karthik Ramasamy   +4 more
wiley   +1 more source

Giant Meckel's Diverticulum Mimicking Crohn's Disease: Double‐Stricture Deception

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
Yongli Li, Tian He, Ping Wan, Xiangji Li
wiley   +1 more source

Computational Study of Drug Delivery Systems with Radionuclide and Fluorescence Imaging Modalities. III. Doxorubicin Delivery Systems Based on Albumin and Lysozyme

East European Journal of Physics
This study investigates the development of advanced protein-based drug delivery systems for doxorubicin (DOX) by integrating lysozyme into albumin-based carriers, incorporating both radionuclide (technetium-99m complexes) and fluorescence (near-infrared ...
V. Trusova, U. Malovytsia, P. Kuznietsov, I. Yakymenko, I. Karnaukhov, A. Zelinsky, B. Borts, I. Ushakov, L. Sidenko, G. Gorbenko   +9 more
doaj   +1 more source

SUCCESSFUL DIAGNOSIS OF PULMONARY ALVEOLAR MICROLITHIASIS BY A NEW MODALITY

Pakistan Journal of Medicine and Dentistry, 2019
Pulmonary alveolar microlithiasis is a rare disease with an almost unheard of pathogenesis. With very few cases to document worldwide, predominantly being discovered in Turkey, Italy, and America, it has been nearly impossible to determine a concrete ...
admin pjmd, Ashok Kumar, Maria Malik, Mehroze Rehman, Waliya Badar Hossain, Rubaab Majida Mohammed, Nadeem Rizvi   +6 more
doaj  

Cyclopentadienyl Complexes of Technetium

Molecules
The number of structurally investigated cyclopentadienyl (Cp−) complexes of technetium is limited in contrast to the situation with its heavier homolog, rhenium.
Ulrich Abram, Maximilian Roca Jungfer
doaj   +1 more source

Reduced uptake of the proliferation-seeking radiotracer technetium-99m-labelled pentavalent dimercaptosuccinic acid in a 47-year-old woman with severe breast epithelial hyperplasia taking ibuprofen: a case report

Journal of Medical Case Reports, 2010
Introduction Recent studies have reported a risk reduction in the progression of benign breast disease to breast carcinoma through COX-2 pathways. Case presentation We present a case of severe epithelial hyperplasia in a 47-year-old woman with increased ...
Marinopoulos Spyridon G, Dimitrakakis Konstantinos E, Stipsanelli Aikaterini J, Ptohis Nikolaos D, Sotiropoulou Maria G, Tsaroucha Angeliki G, Valsamaki Pipitsa N, Sotiropoulou Evangelia K, Papantoniou Vassilios J, Tsiouris Spyridon T, Antsaklis Aris J   +10 more
doaj   +1 more source

^99mTc Labelling Strategies for the Development of Potential Nitroimidazolic Hypoxia Imaging Agents

Inorganics, 2019
Technetium-99m has a rich coordination chemistry that offers many possibilities in terms of oxidation states and donor atom sets. Modifications in the structure of the technetium complexes could be very useful for fine tuning the physicochemical and ...
Javier Giglio, Ana Rey
doaj   +1 more source

Parathyroid imaging with technetium-99m sestamibi

Biomedicine & Pharmacotherapy, 2000
The accurate identification of the location of hyperfunctioning parathyroid nodules is essential to the effective surgical treatment of hyperparathyroidism. Radionuclide imaging has played an important role in the detection of pathological parathyroid nodules.
H, Fujii, A, Kubo
openaire   +2 more sources