Results 61 to 70 of about 22,718 (165)

Development of a method for preparing octreotide derivative for diagnosis of neuroendocrine tumors

Бюллетень сибирской медицины, 2019
Currently the development of technologies for labeling somatostatin with technetium-99m for diagnosing radionuclide neuroendocrine tumors is under way. Somatostatin analogues are binded with technetium99m only by the preliminary addition of a chelating ...
M. S. Larkina, E. V. Podrezova, O. D. Bragina, E. A. Tagirova, V. I. Chernov, M. S. Yusubov, E. A. Nesterov, V. S. Skuridin, S. V. Krivoshchekov, E. A. Yanovskaya, R. V. Gurto, M. V. Belousov   +11 more
doaj   +1 more source

Delayed Aggressive Local Recurrence of Chondroblastic Osteosarcoma 3 Years After an Excellent Pathological Response: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Late recurrence of osteosarcoma after a prolonged disease‐free interval is an uncommon but significant clinical challenge, representing a failure of primary therapy to eradicate microscopic residual disease. We present the case of a 19‐year‐old male diagnosed with chondroblastic osteosarcoma of the proximal tibia who was treated with standard ...
Abdul Hannan, Bilal Aslam, Natasha Hastings, Deepa Lachhman Das, Zahra Sania, Marium Mansoor, Fazeela Bibi, Khalil El Abdi, Samreen Najeeb, Kristen Batten, Manisha Kumari, Said Hamid Sadat   +11 more
wiley   +1 more source

Current Uses for Medical Imaging With Orthopaedic Implant Technology

Journal of Orthopaedic Research, Volume 44, Issue 1, January 2026.
ABSTRACT Musculoskeletal applications have been at the forefront of medical imaging since the first‐ever x‐ray was taken of a hand. Radiography remains routine in orthopaedics for surgical planning and diagnosing implant complications. Fluoroscopy is used to guide intra‐operative implant placement and to assess kinematics of different implants ...
Jordan S. Broberg, Matthew G. Teeter
wiley   +1 more source

Severe Hypercalcemia and Confusion in a Middle‐Aged Male: The Hidden Diagnosis of Parathyroid Carcinoma

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Parathyroid cancer (PC) is one of the rarest causes of primary hyperparathyroidism (PHPT), typically exhibiting an indolent course but presenting with more severe symptoms compared to its benign counterparts. The diagnosis is most often made postoperatively through histopathological examination; however, certain clinical and biochemical features may ...
Helena Fahmi, Mahmoud Karaki, Fatima Yasmin, Layal Akl, Paola Atallah, Osamu Isozaki   +5 more
wiley   +1 more source

Synthesis and Biological Evaluation of Novel Mixed-Ligand ^99mTc-Labeled Anthraquinone Complexes as Potential DNA-Targeted Imaging Agents

Inorganics
Anthraquinones are molecules with numerous biological properties that can act as DNA intercalators and topoisomerase IIa inhibitors. In this work, the development of technetium-99m radiotracers was pursued via the technetium-tricarbonyl “2 + 1” mixed ...
Theofanis Matthaios Migkos, Pigi Glykofridi, Georgios Paparidis, George Psomas, Ioannis S. Vizirianakis, Catherine Gabriel, Dimosthenis Sarigiannis, Ioannis Iakovou, Dionysia Papagiannopoulou   +8 more
doaj   +1 more source

Brown Tumors Mimicking Skeletal Metastases: A Diagnostic Pitfall in Primary Hyperparathyroidism

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Brown tumors are rare but important manifestations of primary hyperparathyroidism (PHPT). These benign, fibrotic, and erosive bony lesions result from localized rapid osteoclastic activity driven by excessive parathyroid hormone levels. Although brown tumors are considered one of the most pathognomonic signs of PHPT, they are infrequently ...
Uzma Akbar, Osama Ahmad, Fatima Sajjad, Khawar Saeed, Umer Dawar, Muhammad Salman Shah, Abdullah Afridi, Kamil Ahmad Kamil   +7 more
wiley   +1 more source

Fifth‐Time Recurrence of Dermatofibrosarcoma Protuberans at Distinct Sites: A Rare Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Dermatofibrosarcoma protuberans is a rare dermal sarcoma with high local recurrence and rare metastasis. Our case highlights unusually frequent recurrences at different trunk sites over 8 years, including fibrosarcomatous transformation and nodal metastasis, underscoring the need for vigilant long‐term surveillance and tailored management.
Hamna Tariq, Hadiya Javed, Mohammed Hammad Jaber Amin   +2 more
wiley   +1 more source

Computational Study of Drug Delivery Systems with Radionuclide and Fluorescence Imaging Modalities. III. Doxorubicin Delivery Systems Based on Albumin and Lysozyme

East European Journal of Physics
This study investigates the development of advanced protein-based drug delivery systems for doxorubicin (DOX) by integrating lysozyme into albumin-based carriers, incorporating both radionuclide (technetium-99m complexes) and fluorescence (near-infrared ...
V. Trusova, U. Malovytsia, P. Kuznietsov, I. Yakymenko, I. Karnaukhov, A. Zelinsky, B. Borts, I. Ushakov, L. Sidenko, G. Gorbenko   +9 more
doaj   +1 more source

^99mTc Labelling Strategies for the Development of Potential Nitroimidazolic Hypoxia Imaging Agents

Inorganics, 2019
Technetium-99m has a rich coordination chemistry that offers many possibilities in terms of oxidation states and donor atom sets. Modifications in the structure of the technetium complexes could be very useful for fine tuning the physicochemical and ...
Javier Giglio, Ana Rey
doaj   +1 more source

SUCCESSFUL DIAGNOSIS OF PULMONARY ALVEOLAR MICROLITHIASIS BY A NEW MODALITY

Pakistan Journal of Medicine and Dentistry, 2019
Pulmonary alveolar microlithiasis is a rare disease with an almost unheard of pathogenesis. With very few cases to document worldwide, predominantly being discovered in Turkey, Italy, and America, it has been nearly impossible to determine a concrete ...
admin pjmd, Ashok Kumar, Maria Malik, Mehroze Rehman, Waliya Badar Hossain, Rubaab Majida Mohammed, Nadeem Rizvi   +6 more
doaj