Results 41 to 50 of about 58,994 (309)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Sentinel lymph node biopsy in early stage cervical cancer: A meta‐analysis

open access: yesCancer Medicine, 2021
Background The aim of this study was to determine the specific side detection rate of the sentinel lymph node biopsy and the accuracy in predicting lymph node metastasis in early stage cervical cancer.
Xinyue Zhang   +5 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Comparison of technetium-99m IgG with technetium-99m red blood cells labeling in cardiac blood-pool scintigraphy: A preliminary study [PDF]

open access: yes, 2011
This first clinical prospective study was conducted to use of technetium-99m immunoglobulin G (99mTc-IgG) as compared with autologous 99mTc-red blood cells (RBC) in gated blood pool ventriculography.
Amini, A.   +7 more
core  

Alopecia, ascites, and incomplete regeneration after 85 to 90 per cent liver resection [PDF]

open access: yes, 1975
A nineteen year old female underwent 85 to 90 per cent partial hepatectomy to treat a minimal deviation hepatoma. Observations afterwards suggested that the limit of resection compatible with survival had been reached.
Corman, JL   +4 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Bioimaging comparison between synthesized carbon quantum dots and nanodiamonds [PDF]

open access: yesNanomedicine Journal
Objective(s): Scientists have been focused on finding access to the potential of different materials, incredibly natural substances. This work compared two categories of nanoscale materials based on carbon sources, including carbon quantum dots (C-QDs ...
Somayeh Marouzi   +3 more
doaj   +1 more source

Reactions of technetium hexafluoride with nitric acid, nitrosyl fluoride, and nitryl fluoride [PDF]

open access: yes, 1970
Stoichiometry of technetium hexafluoride reactions is studied. Magnetic properties and infrared spectra of reaction products are studied and compared with those of analogous complexes of the hexafluorides of tungsten, rhenium, and ...
Holloway, J. H., Selig, H.
core   +1 more source

A high-throughput ab initio review of platinum-group alloy systems [PDF]

open access: yes, 2014
We report a comprehensive study of the binary systems of the platinum group metals with the transition metals, using high-throughput first-principles calculations.
Curtarolo, Stefano   +3 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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