Results 1 to 10 of about 1,430 (119)

From radiolabeling to receptor quantification: preclinical assessment of [99mTc]Tc-carvedilol as a cardiac β-adrenoceptor probe [PDF]

Frontiers in Pharmacology
IntroductionAccurate cardiac adrenoceptor assessment is crucial for managing cardiovascular diseases. This study introduces a novel radiotracer, technetium-99m-labeled carvedilol ([99mTc]Tc-carvedilol), which advances non-invasive cardiac receptor ...
Hala F. Azhari
doaj   +2 more sources

Pitfalls of DualTracer 99m-Technetium (Tc) Pertechnetate and Sestamibi Scintigraphy before Parathyroidectomy: Between Primary-Hyperparathyroidism-Associated Parathyroid Tumour and Ectopic Thyroid Tissue

Medicina, 2023
Diagnosis of primary hyperparathyroidism (PHP) is based on blood assessments in terms of synchronous high calcium and PTH (parathormone), but further management, particularly parathyroid surgery that provides the disease cure in 95–99% of cases, requires
Mara Carsote, Mihaela Stanciu, Florina Ligia Popa, Oana-Claudia Sima, Eugenia Petrova, Anca-Pati Cucu, Claudiu Nistor   +6 more
doaj   +3 more sources

Severe Hypercalcemia and Confusion in a Middle-Aged Male: The Hidden Diagnosis of Parathyroid Carcinoma [PDF]

Case Reports in Endocrinology
Parathyroid cancer (PC) is one of the rarest causes of primary hyperparathyroidism (PHPT), typically exhibiting an indolent course but presenting with more severe symptoms compared to its benign counterparts.
Helena Fahmi, Mahmoud Karaki, Fatima Yasmin, Layal Akl, Paola Atallah   +4 more
doaj   +2 more sources

Diagnostic value of Tc-99m-MIBI SPECT/CT in parathyroid carcinoma with lung metastasis: a case report and literature review [PDF]

Frontiers in Oncology
PurposeParathyroid carcinoma (PC) is an extremely rare disease, typically presenting with marked elevations of serum calcium concentrations and associated with significantly increased parathyroid hormone (PTH) levels.
Yirong Zhu, Yirong Zhu, Lian Wang, Jiaxi You, Shengming Deng, Yizhen Shi, Zengli Liu, Zhihui Hong, Zhihui Hong, Zhihui Hong, Zhihui Hong   +10 more
doaj   +2 more sources

Successful detection and removal of a functional parathyroid adenoma in a pony using technetium Tc 99m sestamibi scintigraphy. [PDF]

J Vet Intern Med, 2014
Tomlinson JE, Johnson AL, Ross MW, Engiles JB, Levine DG, Wisner WA, Sweeney RW.   +6 more
europepmc   +4 more sources

Radioactive Parathyroid Adenomas on Sestamibi Scans: Low Parathyroid Hormone Secretory Potential and Large Volume [PDF]

Endocrinology and Metabolism, 2021
Background We investigated the clinical characteristics of parathyroid adenomas according to radioactivity on 99mTc-methoxyisobutylisonitrile (99mTc-MIBI) single-photon emission computed tomography/computed tomography (SPECT/CT) in primary ...
Sung Hye Kong, Jung Hee Kim, Sang Wan Kim, Chan Soo Shin   +3 more
doaj   +1 more source

Evaluating Estimated Dose outside the Patients Undergoing Myocardial Perfusion Imaging with 99mTc-MIBI [PDF]

Iranian Journal of Medical Physics, 2023
Introduction: It is important that estimated doses from patients administered radiopharmaceuticals in nuclear medicine by hospital staff but other people in connection to patients need radiation protection.
amir reza khorasanchi, Esmat Ramezanzadeh, Azam eskandari, Erfan saatchian, mahmoodreza yahyaei   +4 more
doaj   +1 more source

Enhanced Efficacy of Radiopharmaceuticals When Using Technetium-99m-Labeled Liposomal Agents: Synthesis and Pharmacokinetic Properties

Biomedicines, 2022
Challenges posed by the retention of radiopharmaceuticals in unintended organs affect the quality of patient procedures when undergoing diagnostics and therapeutics. The aim of this study was to formulate a suitable tracer encapsulated in liposomes using
Anfal M. Alkandari, Yasser M. Alsayed, Atallah M. El-Hanbaly   +2 more
doaj   +1 more source

Technetium-99m Radiopharmaceuticals for Ideal Myocardial Perfusion Imaging: Lost and Found Opportunities

Molecules, 2022
The favorable nuclear properties in combination with the rich coordination chemistry make technetium-99m the radioisotope of choice for the development of myocardial perfusion tracers.
Alessandra Boschi, Licia Uccelli, Lorenza Marvelli, Corrado Cittanti, Melchiore Giganti, Petra Martini   +5 more
doaj   +1 more source

Measurement of technetium-99m sestamibi signals in rats administered a mitochondrial uncoupler and in a rat model of heart failure. [PDF]

PLoS ONE, 2015
BACKGROUND:Many methods have been used to assess mitochondrial function. Technetium-99m sestamibi ((99m)Tc-MIBI), a lipophilic cation, is rapidly incorporated into myocardial cells by diffusion and mainly localizes to the mitochondria.
Akira Kawamoto, Takao Kato, Tetsuo Shioi, Junji Okuda, Tsuneaki Kawashima, Yodo Tamaki, Shinichiro Niizuma, Yohei Tanada, Genzou Takemura, Michiko Narazaki, Tetsuya Matsuda, Takeshi Kimura   +11 more
doaj   +1 more source