Results 31 to 40 of about 1,468 (156)

Preoperative Technetium Tc 99m Sestamibi SPECT Imaging in the Management of Primary Hyperparathyroidism in Patients With Concomitant Multinodular Goiter [PDF]

open access: yesArchives of Surgery, 2005
Preoperative parathyroid and thyroid imaging using technetium Tc 99m sestamibi scintigraphy-single-photon emission computed tomography (Tc 99m MIBI SPECT) and technetium Tc 99m sodium pertechnetate, respectively, in patients with parathyroid adenomas and concomitant multinodular goiters enables the selection of those suitable for minimally invasive ...
Mordechai, Lorberboym   +2 more
openaire   +2 more sources

From [99mTc]pertechnetate to [99mTc]sestamibi: Dissection of a Complex Reaction Sequence Using Radio-LC-MS

open access: yesMolecules
[99mTc]sestamibi ([99mTc][Tc(MIBI)6]+; MIBI = 2-methoxybutylisonitrile) is a clinically established myocardial perfusion SPECT tracer. Its one-pot kit-based synthesis from [99mTc]pertechnetate ([99mTc][TcO4]−) is complex, involving a 6-oxidation state ...
Joana do Mar Ferreira Machado   +9 more
doaj   +1 more source

Economic analysis including long-term risks and costs of alternative diagnostic strategies to evaluate patients with chest pain

open access: yesCardiovascular Ultrasound, 2008
Background Diagnosis costs for cardiovascular disease waste a large amount of healthcare resources. The aim of the study is to evaluate the clinical and economic outcomes of alternative diagnostic strategies in low risk chest pain patients.
Pizzi Carmine   +4 more
doaj   +1 more source

The Ectopic Parathyroid Adenoma [PDF]

open access: yesArchives of Otolaryngology–Head & Neck Surgery, 1998
To evaluate the cumulative costs of failure to identify the ectopic parathyroid adenoma when exploration without preoperative localization is performed and to compare these costs with the expenses of routine preoperative localization in every patient.A consecutive series of 59 patients with primary hyperparathyroidism studied with preoperative scans ...
R A, Sofferman, M H, Nathan
openaire   +2 more sources

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh   +7 more
wiley   +1 more source

Relative Contributions of Technetium Tc 99m Sestamibi Scintigraphy, Intraoperative Gamma Probe Detection, and the Rapid Parathyroid Hormone Assay to the Surgical Management of Hyperparathyroidism [PDF]

open access: yesArchives of Surgery, 2000
Technetium Tc 99m sestamibi scintigraphy, intraoperative gamma probe detection, and the rapid parathyroid hormone assay have been used to permit a directed operation in patients with hyperparathyroidism. We hypothesized that the coordinated use of these techniques might be particularly useful in patients who require a second operation for ...
A P, Dackiw   +8 more
openaire   +2 more sources

Disproportionate Elevated Troponin T Without Clinical Ischemia: A Diagnostic Challenge in the Emergency Department

open access: yesCase Reports in Medicine, Volume 2026, Issue 1, 2026.
Background Cardiac troponins (cTns) are essential for evaluating chest pain, but elevated levels can arise from noncardiac causes or laboratory artifacts. Confirmatory testing for assay interference is often unavailable for false‐positive cases, complicating diagnosis and management.
Bryan Nicolalde   +5 more
wiley   +1 more source

Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case Report

open access: yesAnnals of Internal Medicine: Clinical Cases
Because of their similarities with parathyroid carcinomas, atypical parathyroid adenomas constitute a challenge for pathologists. The diagnosis of this kind of parathyroid tumor also can be difficult for clinicians because of the low accuracy of imaging ...
Paola G. Donoso Naranjo   +3 more
doaj   +1 more source

GAMMAGRAFÍA CON 99TC-MIBI PARA DETERMINAR LA EFECTIVIDAD DE LA HEBERQUINASA PARA REPERFUNDIR LA ARTERIA RELACIONADA CON EL INFARTO / 99tc-mibi gammagraphy to determine Heberkinase effectiveness in the reperfusion of the infarction-related artery [PDF]

open access: yesCorSalud, 2010
Resumen Introducción y objetivos: La utilización de técnicas nucleares para la determinación de la permeabilidad de la arteria relacionada con el infarto, es de gran importancia clínica.
Marilyn Ramírez Méndez   +6 more
doaj  

Brown Tumors Mimicking Skeletal Metastases: A Diagnostic Pitfall in Primary Hyperparathyroidism

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Brown tumors are rare but important manifestations of primary hyperparathyroidism (PHPT). These benign, fibrotic, and erosive bony lesions result from localized rapid osteoclastic activity driven by excessive parathyroid hormone levels. Although brown tumors are considered one of the most pathognomonic signs of PHPT, they are infrequently ...
Uzma Akbar   +7 more
wiley   +1 more source

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