Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Shot mechanical analysis according to shooting performance in youth basketball players
In basketball, shooting stands out as a vital technique directly affecting the game results. Identifying shooting mechanics early in a basketball player's career can significantly develop shooting performance in subsequent years.
Fatih Kılınç, Ömer Pamuk
doaj +1 more source
Deep Insights into Heavy Oil Upgrading Using Supercritical Water by a Comprehensive Analysis of GC, GC-MS, NMR, and SEM-EDX with the Aid of EPR as a Complementary Technical Analysis. [PDF]
Djimasbe R +12 more
europepmc +1 more source
Solar heating and cooling technical data and systems analysis [PDF]
The acquisition and processing of selected parametric data for inclusion in a computerized Data Base using the Marshall Information Retrieval and Data System (MIRADS) developed by NASA-MSFC is discussed.
Christensen, D. L.
core +3 more sources
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Technical Factors Affecting an Immunoelectrophoretic Reference System for Analysis of Mycobacterial Antigens [PDF]
Bernard W. Janicki +2 more
openalex +2 more sources
FACT CORRELATION FOR INTELLIGENCE ANALYSIS. VOLUME 2. ANALYSIS OF TECHNICAL PROBLEMS [PDF]
FEDERAL ELECTRIC CORP PARAMUS NJ
openalex +1 more source
Technical Guide for the Analysis of Microenterprise Financial Institutions [PDF]
The purpose of this technical guide is to provide a standard format for the analysis of institutions that provide financial services to the microenterprise sector.
Mark Flaming +2 more
core +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Chartists and Fundamentalists in the Currency Market and the Volatility of Exchange Rates [PDF]
The purpose of this paper is to implement theoretically, the empirical observation that the relative importance of fundamental versus technical analysis in the foreign exchange market depends on the planning horizon.
Bask, Mikael
core +1 more source

