Results 151 to 160 of about 25,814,481 (206)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Women's basketball vs. United Tribes Technical College (2/9/2005)
Video of women's basketball game against United Tribes Technical College, played February 9, 2005. Time: 01:07:50 (1 hour, 7 minutes, 50 seconds)
United Tribes Technical College Athletic Department
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ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Women's basketball vs. United Tribes Technical College (2/12/2004)
Video of women's basketball game against United Tribes Technical College, played February 12, 2004. Time: 01:18:18 (1 hour, 18 minutes, 18 seconds)
United Tribes Technical College Athletic Department
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Men's basketball vs. United Tribes Technical College (2/9/2005)
Video of men's basketball game against United Tribes Technical College, played February 9, 2005. Time: 01:17:38 (1 hour, 17 minutes, 38 seconds)
United Tribes Technical College Athletic Department
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Men's basketball vs. United Tribes Technical College (2/25/2004)
Video of men's basketball game against United Tribes Technical College, played February 25, 2004. Time: 01:51:52 (1 hour, 51 minutes, 52 seconds)
United Tribes Technical College Athletic Department
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