Results 51 to 60 of about 196,693 (264)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ceramics of the Old Bering Sea Culture from the Kozhevnikov Cliff Site (Cape Schmidt): Features of Pottery Technology

Нижневолжский археологический вестник
During the excavations of a dugout at the Kozhevnikov Cliff site (Cape Schmidt), N.N. Dikov obtained a collection of pottery vessels of the Old Bering Sea culture (fourteen specimens).
Dmitry V. Selin, Alexander I. Lebedintsev, Pavel S. Grebenyuk, Alexander Yu. Fedorchenko   +3 more
doaj   +1 more source

Pottery-making technology in the population of the transitional period between the Bronze and Iron Ages in the settlement of Mergen 6 of the Lower Ishim River basin [PDF]

Вестник археологии, антропологии и этнографии
Here, we present the results of study of pottery skills in communities of the transitional period from the Bronze Age to the Early Iron Age, who lived on the territory of the settlement of Mergen 6 in the Lower Ishim River region (Western Siberia ...
Ilyushina V.V., Zimina O.Yu.
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A Sector Analysis for RFID Technologies: Fundamental and Technical Analysis for Financial Decision Making Problems [PDF]

, 2009
Automatic identification technologies have been used in a wide range of applications for reducing the amount of time and labor needed to input data and improving data accuracy. As an important automatic identification technology, radio frequency identification (RFID) technologies allow contactless reading and these technologies are particularly ...
Kasap, S., Testik, M. C., Yüksel, E., Kasap, Nihat   +3 more
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Vessel from a Unique Burial of the Osinovoe Ozero Culture of the Western Amur Region: Technology and Chronology

Вестник Новосибирского государственного университета. Серия: история, филология
Purpose. A unique burial site from the Osinovoe Ozero culture was discovered under a rock overhang in the Western Amur region. One ceramic vessel in particular stands out in this collection, decorated with applied rollers that form a spiral ornament with
D. V. Selin, S. V. Kovalenko, L. N. Mylnikova   +2 more
doaj   +1 more source