Results 61 to 70 of about 196,693 (264)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The paper presents the results of the technical and technological analysis of the ceramic material obtained in the course of the study of the monuments of the Late Bronze Age of the Beregovsky аrchaeological microdistrict located in the Meleuzovsky ...
V.I. Mukhametdinov, E.V. Ruslanov
doaj
Ceramic Complex of Zhigulevsk I Settlement of Imenkovo Culture
The paper aimes to the introduction into scientific circulation of the materials of the Zhigulyovsk I settlement excavation, which was explored in 2017 by the expedition of the Agency for the Preservation of the Historical and Cultural Heritage of the ...
Nikitina Anna V.
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The article presents the results of technical and technological analysis of the Novoilyinsky culture ceramics of the Kama-Vyatka interfluve campsites: Arkul, Sredneye Shadbegovo I, Sredneye Shadbegovo II, Sredneye Shadbegovo III, Sredneye Shadbegovo IV ...
Olga V. Andreeva
doaj +1 more source
Balakhchino VIa Site Neolithic Complex in the Kama Mouth Region
The materials from one of the Neolithic sites of the Middle Volga Region are analyzing by the authors of the paper. Ceramic finds from the site corresponds to the ceramic tradition of the Neolithic Kama culture in terms of the technical and typological ...
Vybornov Aleksandr A. +1 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Archaeological cultures formed at the end of the Bronze Age in the steppe area between the Ob and Irtysh rivers are characterized by a considerable level of variability.
Papin D.V., Stepanova N.F., Fedoruk A.S.
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Health Technology Assessment In Brazil: A Technical Analysis [PDF]
Teich, V. +4 more
openaire +2 more sources

