Results 81 to 90 of about 16,428 (257)

Risks in technical diagnostics

This bachelor thesis deals with the issue of risks in technical diagnostics. The theoretical part of the thesis is divided into two parts. In the first part attention is paid to technical diagnostics in general and its methods.
Machů, Roman
core   +1 more source

Detailed Analytical Characterization of a Bispecific IgG1 CrossMab Antibody of the Knob-into-Hole Format Applying Various Stress Conditions Revealed Pronounced Stability

ACS Omega, 2022
Ingrid Grunert, Katrin Heinrich, Juliane Ernst, Michael Hingar, Alexandre Briguet, Michael Leiss, Manfred Wuhrer, Dietmar Reusch, Patrick Bulau   +8 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Using similarity numbers for the diagnostics of aircraft hydrogenerator

, 2014
In aviation, great emphasis is placed on aircraft safety. The current technical condition of the aircraft and its systems is an important parameter for its airworthiness.
Bencalik, Karol, Karel Tretina, Karol Bencalik, Tretina, Karel   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Off-line technical diagnostics

The bachelor thesis deals with off-line technical diagnostics of rotating machines, focusing primarily on vibrodiagnostics. The thesis presents the general concept of technical diagnostics, its tools and methods, with an emphasis on vibrodiagnostics ...
Felinger, Vojtěch
core   +1 more source

Increasing Reliability and Accuracy of Technical Diagnostics of Asynchronous Motors [PDF]

, 2023
Изложены результаты экспериментальных исследований по технической диагностике асинхронных двигателей. Показана возможность выявления дефектов при расширении спектров вибрации до 5000 Гц или даже до 10000 Гц.
Жобборов, Т. К., Грунтович, Н. В., Петров, И. В., Турсунов, Д. А.   +3 more
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Reliability Improvement of Printed Circuit Boards by Designing Methods for Solder Joint Technical Diagnostics with Application of Acoustic Emission Method

Vìsnik Nacìonalʹnogo Tehnìčnogo Unìversitetu Ukraïni Kììvsʹkij Polìtehnìčnij Ìnstitut: Serìâ Radìotehnìka, Radìoaparatobuduvannâ, 2019
The paper represents technical diagnostics of printed circuit boards in particular their solder joints performed by commonly used through-hole and surface mount technologies.
I. I. Kovtun, J. M. Boiko, S. A. Petrashchuk   +2 more
doaj   +1 more source