Results 121 to 130 of about 3,142,223 (300)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Connecting the unobserved dots : a decomposition analysis of changes in earnings inequality in urban Argentina, 1980-2002 [PDF]

open access: yes
There are several possible explanations for the observed changes in inequality, the returns to education, and the gap between the wages of informal and formal salaried workers in Argentina over the period 1980-2002.
Demombynes, Gabriel, Metzler, Johannes
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

A duration analysis of CONALEP (Mexico's National Technical Professional School) [PDF]

open access: yes
Mexico's National Technical Professional School (Colegio Nacional de Educaci?n Profesional T?cnica, CONALEP) is the largest technical education system in the country. CONALEP serves low-income students at the upper-secondary school level in Mexico. Using
Lopez-Acevedo, Gladys
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

On the development of didactic systems in the context of digital transformation of vocational education (part 1)

open access: yesRUDN Journal of Informatization in Education
Problem statement. The widespread use of modern digital and network technologies in the educational process of professional school has led to the need to analyze innovative experience from the standpoint of general theory and didactics of vocational ...
Irina G. Alyokhina   +6 more
doaj   +1 more source

Social services, human capital, and technical efficiency of smallholders in Burkina Faso: [PDF]

open access: yes
This study applies regression analysis as well as a non-parametric method to survey data from Burkina Faso to analyze the role of human capital in explaining technical efficiency in smallholder agricultural production.
Wouterse, Fleur
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Problem based learning in architectural education [PDF]

open access: yes, 2007
There is limited published research and discussion on pedagogical approaches in architectural education. Problem (or Project) Based Learning is used successfully in other professional disciplines, and, consequently, there have been attempts to utilise ...
Bridges, Alan
core  

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