Results 81 to 90 of about 10,039,556 (320)

Technical and Vocational Education and Training in Italy: Structure and Changes at National and Regional Level [PDF]

Even though the institutional framework is strongly centralised, Italy displays important territorial differences in the education system. Historically, such differences are interwoven with territorial differences both in economic and social development.
Margherita Russo, Paola Mengoli
core  

The Australian Research Quality Framework: A live experiment in capturing the social, economic, environmental, and cultural returns of publicly funded research [PDF]

, 2008
Copyright @ 2008 Wiley Periodicals Inc. This is the accepted version of the following article: Donovan, C. (2008), The Australian Research Quality Framework: A live experiment in capturing the social, economic, environmental, and cultural returns of ...
Allen Consulting Group, Austrian Science Fund (FWF)/European Science Foundation (ESF), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Education, Science and Training (DEST), Department of Innovation, Industry, Science and Research (IISR), Donovan, Donovan, Donovan, Donovan, Martin, Research Quality Framework Technical Working Group on Research Impact (TWGRI), Spaapen, Wooding   +21 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Research and Prediction of the Application of Multimedia Teaching Aid in Teaching Technical Education on the 2nd Level of Primary Schools

Informatics in Education, 2011
The purpose and the main aim of the pedagogic experiment were to practically verify the success of Multimedia Teaching Aid (MTA) in conditions of primary schools.
Ján STEBILA
doaj   +1 more source

Career and Technical Education (CTE): A Primer [PDF]

, 2014
[Excerpt] Career and technical education (CTE), sometimes referred to as vocational education, provides occupational and non-occupational preparation at the secondary, postsecondary, and adult education levels.
Dortch, Cassandria
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

External Return to Education in Poland [PDF]

In the article social rate of return to education is considered. As is pointed out in various research papers social return rate exceeds the pure technical rate of return by considerable margin.
Strawinski, Pawel
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

TEKNİK EĞİTİM FAKÜLTESİ ÖĞRETMEN ADAYLARININ ÖĞRETMENLİK BECERİLERİ

Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2006
Bu çalışmada amaç; Düzce Teknik Eğitim Fakültesi son sınıf öğrencilerinin öğretmenlik becerilerini uygulama düzeylerini belirlemektir. Bu öğrenciler sekizinci son dönemde öğretmenlik uygulamasıdersinde öğretmenlik becerilerini okullara uygulamaya ...
Abdurrahman Kılıç, Hamit Saruhan
doaj