Results 171 to 180 of about 14,757,385 (333)

Technical Reports.

open access: yesNature biotechnology
Technical reports will be publisedh to the project webiste and that of the individual consortium members. Additionally peer reviewed publications may be submitted.
  +6 more sources

Technical Report

open access: yes
Technical report on the structure of the ...
openaire   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Erratum: Lumbocaval Shunt for Idiopathic Intracranial Hypertension: A Technical Report and Case Series: Corrigendum. [PDF]

open access: yesNeurosurg Pract
Sujijantarat N   +15 more
europepmc   +1 more source

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