Results 91 to 100 of about 387,458 (358)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Effects of VR technical interaction and acceptance on rural cultural identity: The mediating role of embodied cognition and flow experience

open access: yesTelematics and Informatics Reports
With the development of digital media, an increasing number of new technologies are being used in cultural communication, and virtual reality (VR) technology for cultural communication has become a modern tool of transmission.
Xiuyu Lin   +5 more
doaj   +1 more source

Development and Application of Lightweight High-strength Metal Materials

open access: yesMATEC Web of Conferences, 2018
This article reviews the performance, alloy composition and the development of advanced lightweight high-strength materials such as high-strength steels, high-strength aluminum alloys, high-strength magnesium alloys, and titanium alloys.
Pan He
doaj   +1 more source

Research on taking the road of Chinese path to modernization well——Based on a new development perspective [PDF]

open access: yesSHS Web of Conferences
The fact of the matter is that Chinese modernization is not only a great creation of CPC, but also a path we must take to realize the rejuvenation of the Chinese nation.
Yang Gu, Hua Liu
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newly credentialed veterinary technician: perceptions, realities, and career challenges

open access: yesFrontiers in Veterinary Science
Previous research has shown that when comparing psychological wellbeing between credentialed veterinary technicians and human registered nurses, high levels of burnout and distress were noted within the veterinary technician population.
Addie R. Reinhard   +5 more
doaj   +1 more source

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