Results 151 to 160 of about 373,674 (263)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Polk County, School Board of and American Federation of State, County & Municipal Employees (AFSCME), AFL-CIO, Local 2227 (2004) [PDF]

, 2004

core   +1 more source

Comparative Evaluation of Ultrasound Measurement of the Plantar Fascia Between Expert and Novice Technicians. [PDF]

Healthcare (Basel)
Larriba-Pérez A, Ledesma-Alcázar MC, García-Martínez MT, García-Gomariz C, Blasco JM, Cobos-Moreno P.   +5 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Implementation of a Continuous Video Monitoring Program to Decrease Inpatient Falls in a Long-Term Acute Care Hospital Setting: A Prospective Observational Cohort Study. [PDF]

Am J Nurs
Kalafus L, Hrdlicka HC, Lombardi J, Proctor S, Napolitano J, Morrill N.   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

The value of a good doctor. [PDF]

J R Soc Med
Ross N.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Encouraging higher recruitment to technician engineering training: project final report [PDF]

, 2001
Shirley, Tony, Weiss, Claire
core  

Impact of Pharmacy Technicians on Clinician and Nurse Work Experience in Primary Care. [PDF]

Ann Fam Med
McNamara A, Chan LLS, Willard-Grace R, Kenison TC, Grumbach K.   +4 more
europepmc   +1 more source