Results 51 to 60 of about 295,920 (304)

The Veterans Affairs Neuropathy Scale: A Reliable, Remote Polyneuropathy Exam. [PDF]

, 2019
Introduction: Polyneuropathy (PN) complaints are common, prompting many referrals for neurologic evaluation. To improve access of PN care in distant community clinics, we developed a telemedicine service (patient-clinician interactions using real-time ...
Jamal, Nasheed I, Ong, Michael K, Saliba, Debra, Wilson, Andrew M   +3 more
core  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

CONTACT SENSITIZATION TO METHACRYLIC MONOMERS AMONG DENTAL TECHNICIAN STUDENTS IN RELATION TO DURATION OF EDUCATIONAL EXPOSURE [PDF]

Journal of IMAB, 2019
Purpose: Sensitization to methacrylic monomers is a significant problem in dental occupational exposures. The purpose of the present study was to evaluate the dynamics in contact sensitization incidence to methacrylic monomers during the educational ...
Maya Lyapina, Todor Kundurjiev, Karolina Lyubomirova, Evgeny Stanev, Zaharina Savova   +4 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Patient Care Technician Staffing in US Hemodialysis Facilities: An Ecological Study

Kidney Medicine
Rationale & Objective: Technicians caring for patients receiving dialysis play a critical, frontline role in the care of patients receiving dialysis in the United States.
Laura C. Plantinga, Megan Urbanski, Courtney Hoge, Fran Rickenbach, Clarica Douglas-Ajayi, Jennifer Craft Morgan, Alexis A. Bender, Bernard G. Jaar   +7 more
doaj   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

On some tree species, annual sprays may control western poplar clearwing moth

California Agriculture, 1994
The western poplar clearwing moth, a serious pest to many species of western ornamental trees, can cause limb breakage or tree death in severe cases.
Walter Bentley, John Karlik, Woody Affleck   +2 more
doaj   +1 more source

Dental Technicians' Pneumoconiosis

Internal Medicine, 2017
A 40-year-old female dental technician visited our hospital for the investigation of a chest X-ray abnormality. Chest computed tomography demonstrated centrilobular nodules and lung volume reduction, and her serum KL-6 level was elevated. A histological analysis of the specimens obtained on a surgical lung biopsy showed peribronchiolar fibrosis with ...
Takashi Nouno, Shigeki Shimizu, Mitsuru Yokoyama, Yoshiaki Zaizen, Masaki Tominaga, Masaki Okamoto, Ken Masuda, Tomotaka Kawayama, Satoshi Sakamoto, Tomoaki Hoshino, Masayuki Nakamura, Chiyo Yano   +11 more
openaire   +4 more sources