Results 111 to 120 of about 10,997,608 (305)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
ICT Update 74: ICT4Ag - préparer le terrain
, 2016 ICT Update est un magazine bimestriel édité par le CTA et disponible sur Internet (http://ictupdate.cta.int), en version papier et sous forme d'une newsletter diffusée par e-mail.
Centre Technique de Coopération Agricole et Rurale
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
THE IMPORTANCE OF OPTIMIZATION OF LATTICE STRUCTURES FOR BIOMEDICAL APPLICATIONS
Nonconventional Technologies Review, 2019 The paper describes the importance of optimization of lattice structures intended to be used in medical applications. Additive manufacturing process gains an important place in the medical industry due to the ability to obtain complex geometries ...
Luciana Laura Shamieh-Dinca +4 more
doaj
ICT Update 64: Chaînes de valeur
, 2016 ICT Update est un magazine bimestriel édité par le CTA et disponible sur Internet (http://ictupdate.cta.int), en version papier et sous forme d'une newsletter diffusée par e-mail.
Centre Technique de Coopération Agricole et Rurale
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
ICT Update 70: Recherche agricole et TIC
, 2016 ICT Update est un magazine bimestriel édité par le CTA et disponible sur Internet (http://ictupdate.cta.int), en version papier et sous forme d'une newsletter diffusée par e-mail.
Centre Technique de Coopération Agricole et Rurale
core