Results 131 to 140 of about 12,307,103 (335)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Nozzle fabrication technique [PDF]

open access: yes
This invention relates to techniques for fabricating hour glass throat or convergent divergent nozzle shapes, and more particularly to new and improved techniques for forming rocket nozzles from electrically conductive material and forming cooling ...
Wells, Dennis L.
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Restoration Capacity Prediction of Double-Row Capsule Grouting to Control Tunnel Deformation

open access: yesAdvances in Civil Engineering
The double-row capsule grouting (DRCG) is an innovative technique which can restrain the horizontal and vertical tunnel deformations induced by excavation simultaneously.
Xiaopei He   +3 more
doaj   +1 more source

Modeling the Thermoforming Process of a Complex Geometry Based on a Thermo-Visco-Hyperelastic Model

open access: yesJournal of Manufacturing and Materials Processing
The thermoforming process is commonly used in industry for the manufacturing of lightweight, thin-walled products from a pre-extruded polymer sheet. Many simulations have been developed to simulate the process and optimize it with computer tools.
Ameni Ragoubi   +4 more
doaj   +1 more source

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