Results 81 to 90 of about 10,997,608 (305)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Determination of Carbon in Ni-Al Powder by the Pure Chemical Substance Calibration-high Frequency Combustion Infrared Absorption Method

open access: yesYankuang ceshi, 2014
The carbon in Ni-based powder directly influences the property of the material. However, there is no national standard method to determine carbon content in Ni-based powder, according to the wide content range of carbon, different interferences and ...
ZHANG Yong   +6 more
doaj   +2 more sources

Research on virtual memory system based on ARMv7-A architecture

open access: yesDianzi Jishu Yingyong, 2018
As the development trend of integrated, intelligent and low power application in embedded systems, ARM series processors have been widely used in recent years.
Cao Pengpeng, Chen Jia, Zhang Shaofeng
doaj   +1 more source

The Most Significant Change Technique [PDF]

open access: yes, 2009
{Excerpt} The Most Significant Change technique helps monitor and evaluate the performance of projects and programs. It involves the collection and systematic participatory interpretation of stories of significant change emanating from the field level ...
Serrat, Olivier
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Protéger et promouvoir le pastoralisme en Afrique [PDF]

open access: yes, 2016
Le pastoralisme subvient aux besoins de dizaines de millions de personnes. Il utilise au mieux des environnements difficiles et offre de nombreux avantages économiques et sociaux.
Centre Technique de Coopération Agricole et Rurale
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Modelling effluent reuse in the pulp and paper industry to predict consequences on conductivity

open access: yesWater Science and Technology
The objective of this study was to assess, through simulation, conductivity variations in pulp and paper circuits when recycling waste water treatment plant (WWTP) effluent with a view to reducing fresh water use in a tissue mill.
Stephanie Prasse   +3 more
doaj   +1 more source

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