Results 91 to 100 of about 8,946,730 (308)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Techniques to Build and Reuse Assets
, 2008 technique. Section 7.7 describes software architectures, which represent an independent research area. For most of the techniques (where appropriate), a list of enabling methodologies and technologies is presented.
Davide Brugali +2 more
core
Wide Field Multicolor CCD Photometry of the Open Cluster NGC752
Open Astronomy, 2010 The results of CCD photometry in the seven-color Vilnius system of 3058 stars down to V ~ 18.0 mag in a 1.5 square degree field around the cluster NGC 752 are presented.
Zdanavičius J. +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Análisis de las acciones técnicas de los judokas cadetes participantes en el campeonato de España. (Analysis of technical actions of the judoist cadets participating in the judo championship of Spain.) [PDF]
Revista Internacional de Ciencias del Deporte, 2009 ResumenEl entrenamiento del judoka dada su amplia estructura técnica, su dimensión táctica, su estructuración por categorías de peso y la incertidumbre creada por el adversario, muestra diversos y complejos aspectos a considerar, que deben ser analizados
Vicente Carratalá Deval +2 more
doaj
A Statistical Study of the Si IV Resonance Line Parameters in 19 Be Stars
Open Astronomy, 2011 Using the GR model, we analyze the ultraviolet Si IV resonance lines in the spectra of 19 Be stars of different spectral subtypes, in order to detect the presence of absorption components and to analyze their characteristics.
Antoniou A. +4 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
, 2008 Monte Carlo techniques are often the only practical way to evaluate difficult integrals or to sample random variables governed by complicated probability density functions.
F. James (cern, Monte Carlo Techniques
core
Open Astronomy, 2003 Seven-color photometry in the Vilnius system has been obtained for 420 stars down to V = 16 mag in the area containing the overlapping open clusters NGC 1750 and NGC 1758 in Taurus.
Straižys V. +8 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source