Results 81 to 90 of about 8,946,730 (308)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
, 2008 Monte Carlo techniques are often the only practical way to evaluate difficult integrals or to sample random variables governed by complicated probability density functions.
Monte Carlo Techniques
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2011 Monte Carlo techniques are often the only practical way to evaluate difficult integrals or to sample random variables governed by complicated probability density functions.
Monte Carlo Techniques
core
DUDAK KANSERİ HASTALARINDA CERRAHİ VE PATOLOJİYE İLİŞKİN SORUNLAR VE YÖNETİMİ
Journal of Contemporary Medicine, 2021 Giriş: Dudak kanserleri baş boyun bölgesinde ikinci sıklıkta görülen kanserlerdir. Fonksiyonel ve estetik sonuçları ve agresif seyri sebebiyle cerrahi eksizyon sınırları, boyun diseksiyonu tipi ve rekonstrüksiyon seçenekleri gibi klinik yaklaşım tipleri ...
Tuğba Gün Koplay, Mehtap Şen
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
: Laser sources combining techniques
, 2017 International audienceThis paper presents the main techniques used to combine laser sources, in order to increase their level of power. Actually, one can rely on appropriate techniques to add up efficiently, i.e.
Bourdon, Pierre
core +4 more sources
Hydatidiform mole: A sour encounter with a grapy case
Indian Journal of Anaesthesia, 2011 Hydatidiform mole cases are usually uncomplicated. However, few cases can be associated with perioperative complications of a critical nature, which can lead to substantial mortality and morbidity.
Madhuri S Kurdi
doaj +1 more source