Results 121 to 130 of about 481,076 (313)

A Contextual Approach to Technological Understanding and Its Assessment [PDF]

arXiv
Technological understanding is not a singular concept but varies depending on the context. Building on De Jong and De Haro's (2025) notion of technological understanding as the ability to realise an aim by using a technological artefact, this paper further refines the concept as an ability that varies by context and degree.
arxiv  

A Scalable and Automated Framework for Tracking the likely Adoption of Emerging Technologies [PDF]

While new technologies are expected to revolutionise and become game-changers in improving the efficiencies and practises of our daily lives, it is also critical to investigate and understand the barriers and opportunities faced by their adopters. Such findings can serve as an additional feature in the decision-making process when analysing the risks ...
arxiv   +1 more source

Scientific Opinion on the safety and efficacy of formic acid when used as a technological additive for all animal species [PDF]

, 2014

openalex   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Towards Security of Additive Layer Manufacturing [PDF]

arXiv, 2015
Additive Layer Manufacturing (ALM), also broadly known as 3D printing, is a new technology to produce 3D objects. As an opposite approach to the conventional subtractive manufacturing process, 3D objects are created by adding thin material layers over layers. Until recently, they have been used, mainly, for plastic models.
arxiv  

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Tailoring short-range order and dislocation evolution in Cr–Co–Ni medium-entropy alloys: A molecular dynamics study

Materials & Design
The research community has recently been captivated by the atomic-scale short-range order observed in high- and medium-entropy alloys. However, significant challenges persist in improving the mechanical performance through manipulation of the short-range
Asker Jarlöv, Weiming Ji, Rita Babicheva, Yujia Tian, Zhiheng Hu, Hang Li Seet, Liming Tan, Feng Liu, Yong Liu, Mui Ling Sharon Nai, Upadrasta Ramamurty, Kun Zhou   +11 more
doaj  

Particle detection technology for space-borne astroparticle experiments [PDF]

arXiv, 2014
I review the transfer of technology from accelerator-based equipment to space-borne astroparticle detectors. Requirements for detection, identification and measurement of ions, electrons and photons in space are recalled. The additional requirements and restrictions imposed by the launch process in manned and unmanned space flight, as well as by the ...
arxiv  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source