AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of <i>Saccharomyces cerevisiae</i>NBRC 0203 and <i>Lacticaseibacillus rhamnosus</i>NBRC 3425 as a silage additive for all animal species (EM-Agriton B.V.). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +26 more
europepmc +1 more source
A Guide to the Air Quality Act of 1967 [PDF]
Martin, Robert, Symington, Lloyd
core +2 more sources
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of <i>Pediococcus pentosaceus</i>NCIMB 12674 for all animal species (Danstar Ferment AG). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +21 more
europepmc +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Efficiency of Recurrent Genomic Selection in Panmictic Populations. [PDF]
Viana JMS, Silva JPAD, Lopes PS.
europepmc +1 more source
Technological, rheological and sensory characterizations of a yogurt containing an exopolysaccharide extract from Lactobacillus fermentum Lf2, a new food additive [PDF]
Elisa C. Ale +8 more
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Performance and carcass characteristics of Nellore cattle fed a high-concentrate diet with a phytogenic additive blend. [PDF]
Ferracini JG +7 more
europepmc +1 more source

