Results 21 to 30 of about 43,142 (263)
Early cost estimation for additive manufacture [PDF]
Additive Manufacture (AM) is a novel manufacturing method; it is a process of forming components by adding materials. Owing to material saving and manufacturing cost saving, more and more research has been focused on metal AM technologies. WAAM is one AM
Zhai, Yun
core
Supply chain perspective on additive manufacturing
Current research on Additive Manufacturing (AM) has focused primarily on the technological aspects in terms of improving engineering feasibility and product quality. The increasing maturity of AM technology is not going to incrementally provide another
Ma, Shuang +2 more
core +1 more source
Emissions of Volatile Compounds and Solids during Additive Manufacturing by the FFF Method
The rapid development of the additive manufacturing industry is a great opportunity both for the development of the industry in the context of rapid prototyping and for hobbyists using 3D printers at home.
Anna Karwasz +2 more
core +1 more source
Owing to excellent high-temperature mechanical properties, i.e., high heat resistance, high strength, and high corrosion resistance, Ti alloys can be widely used as structural components, such as blades and wafers, in aero-engines.
Xuefeng Ding +7 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Additive manufacturing of Inconel 625 superalloy parts via high pressure cold spray
Cold gas dynamic spray (CGDS) or simply ‘cold spray’ (CS) is an emerging additive manufacturing technique, which is used in repair applications of metal components.
Tan, Adrian Wei Yee +6 more
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

