Results 81 to 90 of about 431,230 (251)

Approaches to calculating the attractiveness of technological projects

Vestnik of Samara University. Economics and Management, 2023
For the selection and further effective implementation of a technological project, it is important to assess its attractiveness. The relevance of the scientific article follows from this request, since it considers the main drawback of the available tools for assessing the investment attractiveness of technological projects. It is important not only to
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

TECHNIQUE AND TECHNOLOGY OF PRODUCTION OF TWO-LAYER ROLLED WIRE SPIRAL CONSTRUCTIONS 2+7 AND 3+9 WITH DIFFERENT STEPS OF DISCHARGING BY LAYS IN ONE TECHNOLOGICAL OPERATION

Литьë и металлургия, 2004
The way of the production of steel wire cord of the two-layer spiral constructions with the different lay paces in one technological operation, developed at RUP ''BMZ”, is presented.
Ju. L. Hudolej
doaj  

Методика аналитического расчета технологических показателей обогащения полезных ископаемых [PDF]

, 2014
Розроблено принцип розрахунків технологічних показників збагачення корисних копалин та сформульовано перелік необхідних математичних моделей для таких розрахунків.Разработан принцип расчета технологических показателей обогащения полезных ископаемых и ...
Левченко, Константин Анатолиевич, Младецкий, Игорь Константинович, Пилов, Петр Иванович   +2 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Application of European approaches to the determination of technological indicators of the best available techniques in the field of wastewater treatment

Водное хозяйство России: проблемы, технологии, управление, 2021
The year 2014 was a turning point in the transition of the main sectors of the Russian economy to a new track of environmental regulation and the introduction of obligations for first category’ s objects of negative environmental impact to receive a ...
Oleg V. Grevtsov, Maksim E. Astrakhanov, Andrey N. Epov   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Finite element modeling of bearing elements technological machines and equipment

MATEC Web of Conferences, 2018
The paper considers the examples of technical production tests to determine the bearing capacity of the structural elements of technological machines and equipment used in various industries and agriculture: the bearing beam of the front axle of the ...
Yevtushenko Sergey I., Alekseev Sergey A., Petrov Igor A., Fedorchuk Vladimir E.   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Can the use of a Facebook group in addition to classroom teaching enhance exam success in a Drug Calculations module? [PDF]

, 2014
A wide range of literature acknowledges the use of e- and traditional learning in the health professions but further research is frequently recommended to explore perceived benefits (Lahti, Hatonen & Valimaki, 2013; Cook et al, 2010) particularly in the ...
Ryan, Gemma Sinead
core