Results 91 to 100 of about 142,381 (311)

Technology Transfers and Knowledge Managementin Developing Economies:Case Study of an Indonesian Manufacturer

open access: yesJournal of Entrepreneurship, Management and Innovation, 2013
International technology transfers are crucial for developing economies since they may operate as one of the key drivers in the economies’ development path. Previous studies have acknowleged some channels of technology transfers for developing economies.
Wahyudi Wibowo
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Assessment of Technological Capabilities for Forming Al-C-B System Coatings on Steel Surfaces by Electrospark Alloying Method. [PDF]

open access: yesMaterials (Basel), 2021
Antoszewski B   +6 more
europepmc   +1 more source

From new to the firm to new to the world. Effect of geographical proximity and technological capabilities on the degree of novelty in emerging economies [PDF]

open access: yes
This paper investigates empirically what it takes for a firm to move from new to the firm to new to the domestic market and new to the world innovations.
Plechero, Monica, Chaminade, Cristina
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

El Valor de la Tecnología: Enfoques Novedosos para su Determinación

open access: yesJournal of Technology Management & Innovation, 2013
Traditionally, Technology valuation has been applied with the financial focus of Project management, focusing on the economical dimension. However, several authors have detected problems in this approach and propose the inclusion of qualitative aspects ...
Claudia Nelcy Jimenez   +1 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Absorptive capacity in technological learning in clean development mechanism projects [PDF]

open access: yes
Technology transfer in Clean Development Mechanism (CDM) projects of the Kyoto Protocol has become one of the important issues addressed both in policy agenda and by academic scholars.
Doranova, Asel   +2 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

New Technological Knowledge Integration in Industries with Long-Wave Innovation: Case Study of Iran Mining and Mineral Industry [PDF]

open access: yesمدیریت صنعتی
Objective Given the escalating complexity of various scientific fields and the competitive nature of markets, the focus on innovation has become crucial for the survival of businesses in the industry.
akbar Mohammadi   +2 more
doaj   +1 more source

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