Results 81 to 90 of about 142,381 (311)
Information platform to improve technological innovation capabilities: role of cloud platform
, 2016 Conceptualizing technological innovation capabilities and cloud platform implementation in the construction management context is still rudimentary.
Huang, Chung-Fah +2 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Branding capability of technology born globals
Journal of Brand Management, 2010 Born globals – young, rapidly internationalising small and medium enterprises – face the significant challenge of building an international brand with scarce resources. In this article, we study international brand strategy and implementation of such firms, and define the components of brand value to customers in technology B2B markets, which many born
Oxtorp, Liliya Altshuler; id_orcid 0000-0002-8825-910X +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Vaccine production industry in Iran and the necessity for policy coherence
Vaccine Research, 2017 Vaccine production industry in Iran and the necessity for policy ...
V Marandi +3 more
doaj
Identifying and ranking key technological capabilities in supply chain sustainability using ISM approach: case of food industry in Iran. [PDF]
Environ Dev Sustain, 2023 Bagheri R, Zomorodi P, Rezaeian A.
europepmc +1 more source
The ICT Component of Technological Diversification: Is there an underestimation of ICT capabilities among the world's largest companies? [PDF]
This empirical paper analyses the importance of information and communications technologies (ICT) in the technological diversification trend among the world's large industrial firms. The objective of the research is twofold.
Sandro Mendonça
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Relationship between Corporate Political Strategy of Public Partnership and Corporate Investment
Foresight and STI GovernanceThis research endeavors to elucidate the dynamics between Corporate Political Activity (CPA) and corporate investment by harnessing advanced econometric techniques, specifically quantile regression and dynamic panel data analysis.
Lin Woon Leong +4 more
doaj +1 more source