Results 51 to 60 of about 109,849 (309)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Cadernos EBAPE.BREste artigo examina as implicações da acumulação de capacidades tecnológicas para diferenças entre empresas em termos de aprimoramento da performance técnico-econômica. Essas questões são examinadas por meio do estudo de caso comparativo em duas empresas
Fernando Ben
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Emergence and Convergence of Technologies as an Intellectual-Innovative Platform for Developing an Explerent Enterprise Management Strategy [PDF]
Problemi EkonomikiThe article substantiates the need for enterprises to transition to an explerent management strategy under conditions of accelerated technological dynamics, emergence, and convergence of scientific and technical directions.
Slastianykova Krystyna I.
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Technology and Human Capabilities in UK Makerspaces [PDF]
Journal of Human Development and Capabilities, 2019 The relationship between technology and human capabilities is an ambivalent one. The same technology can expand capabilities for some users under certain circumstances, whilst diminishing capabilities for others situated differently. In this paper we analyse human capabilities in relation to digital design and fabrication technologies as configured ...
Cian O’Donovan, Adrian Smith
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Internationalization Process and Technological Capability Trajectory of Iguaçu
Journal of Technology Management & Innovation, 2012 This article focuses on the influence of the internationalization process in the evolution of technological capability. This implication was studied in Iguaçu between 1967 and 2009.
Rafael Kuramoto Gonzalez +1 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Technological capabilities in emerging Asia
Oxford Development Studies, 1998 Abstract Given rapid technological and organizational change it appears, nevertheless, that the “emerging” economies of Asia are involved in different ways. Some countries are at the forefront, others on the fringes, of the new technological “paradigm “.
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