Results 41 to 50 of about 60,601 (309)

Inter-fuel substitution in European industry: A random utility approach on industrial heat demand [PDF]

, 2018
As the majority of industrial emissions stems from heat generation, the choice of fuel is, next to energy efficiency, one of the tools to influence climate impact (and security of supply) in industrial energy use.
Fleiter, Tobias, Ernst Worrell, Energy, Resources & Technological Change, Rehfeldt, Matthias, Energy and Resources, Tobias Fleiter, Worrell, Ernst, Matthias Rehfeldt   +7 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Life-cycle assessment of hydrogen utilization in power generation: A systematic review of technological and methodological choices

Frontiers in Sustainability, 2022
Interest in reducing the greenhouse gas emissions from conventional power generation has increased the focus on the potential use of hydrogen to produce electricity.
Dyah Ika Rinawati, Dyah Ika Rinawati, Alexander Ryota Keeley, Alexander Ryota Keeley, Shutaro Takeda, Shunsuke Managi, Shunsuke Managi   +6 more
doaj   +1 more source

Technological Choices for Sustainability

, 2004
This book was made possible by the exceptional support provided by NATO Sci entific and Environmental Division, University of Maribor (Slovenia), Govern ment of the Republic of Slovenia, British and the United States Embassies (Ljubl jana, the Republic ...
Glavi?, Peter, Jain, Ravi, Sikdar, Subhas K.   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Democrazia elettronica. La partecipazione politica ai tempi dei social media [Electronic democracy. Political participation in the time of social media]

Open Journal of Humanities, 2019
Electronic democracy represents a new communication space consisting of a set of tools and technological models aimed at increasing citizens participation in the decision making moments of public action.
Wanda D'Avanzo
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source