Results 61 to 70 of about 60,601 (309)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Technological Choices and Organizational Excellence: the EDF Case
, 2001 International audienceWhat are the relations between the perception of excellence by the organization managers and their technological choices? We study the main technological choices that EDF, the main French electricity producer, has made since its ...
Corbel, Pascal
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
From design to management: a benchmarking process for the energy efficiency of buildings
Techne, 2013 Environmental quality and energy efficiency are strategic objectives which can highlight the ‘effectiveness’ of design and technological choices, as well as the impact of management strategies and user behaviour. Studies show it is possible to narrow the
Judit Kimpian +3 more
doaj +1 more source
The Latent Heterogeneity in Investment Location Choices of Multinational Enterprises [PDF]
The heterogeneity of investing firms is an important determinant of the distribution of foreign direct investment (FDI) location decisions. This paper, for the first time, explicitly allows for firms’ heterogeneity by using a latent class discrete choice
Simona Rasciute, Eric J Pentecost
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How labor market institutions affect technological choices
, 2020 Does the adoption of technological change depend on labor market institutions? The disparities in technology adoption across countries are enormous and are a major factor in explaining poverty.
Samwer, Julia, Chen, Chinchih
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Building Envelope Over-Cladding: Impact on Energy Balance and Microclimate
Buildings, 2015 A considerable part of recent EU policies is currently addressed at developing effective measures to support the transition towards a low carbon society according to the principles and goals of Roadmap to 2050. In this general framework the links between
David Dernie, Jacopo Gaspari
doaj +1 more source
Democratization is the determinant of technological change [PDF]
The purpose of this paper is to analyze the relationship between democracy and technological innovation. The primary findings are that most free countries, measured with liberal, participatory, and constitutional democracy index, have higher ...
Mario Coccia
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