Results 71 to 80 of about 60,601 (309)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Technology assessment for better technological priorities and choices

open access: yes, 1993
This document presents Technology assessment for better technological priorities and choices, of the Eighth Meeting of the Intergovernmental Committee of Experts for Science and Technology Development, held in Addis Ababa (Ethiopia), from 22-26 ...

core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The Effect of Foreign Influence on Conflict and Social Identity in Ethnically Diverse Societies

open access: yesGames
This paper develops a formal model to analyze how foreign interventions—via resource transfers towards mobilization, technological upgrades of the mobilization technology, and various forms of conditional aid—reshape identity choices and conflict ...
Esther Hauk
doaj   +1 more source

Technological choices in the rise of the Meiji cotton-spinning industry c1870-1900

open access: yes, 2007
The central theme of this thesis is the technological choices and the subsequent extraordinary growth of the cotton-spinning industry of Meiji Japan (1868-1912).
Choi, E K
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Self-efficacy beliefs and female choices of scientific-technological studies: a theoretical review of their relationship

open access: yesTeoría de la Educación: Revista Interuniversitaria, 2013
Women are the majority in all levels of education, but there are still differences in the choice of academic options. They are underrepresented in scientific and technological studies at the University.
M.ª del Carmen RODRÍGUEZ MÉNDEZ   +2 more
doaj   +1 more source

Mapping Technological Trajectories as Patent Citation Networks. An application to Data Communication Standards [PDF]

open access: yes
Technical systems, Technological trajectories, Patents, Network analysis, Data ...
Alessandro Nuvolari   +2 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

AN ENERGY PRIMER: FROM THERMODYNAMICS TO THEOLOGY

open access: yesZygon, 2011
Scientific, technological, ethical, and religious issues confronting the human prospect are emerging as we encounter the inevitable shift from fossil to renewable fuels.
doaj   +2 more sources

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