Results 71 to 80 of about 668,692 (311)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Technology alternatives for the SPS [PDF]
, 1980 Emerging technologies may offer advantages over those selected for the reference design adopted for the SPS. While it is not possible to list all the technological innovations that may affect the SPS, it is feasible to develop a systematic methodology ...
Chapman, P. K., Glaser, P.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Building Envelope Over-Cladding: Impact on Energy Balance and Microclimate
Buildings, 2015 A considerable part of recent EU policies is currently addressed at developing effective measures to support the transition towards a low carbon society according to the principles and goals of Roadmap to 2050. In this general framework the links between
David Dernie, Jacopo Gaspari
doaj +1 more source
The economic basis for national science and technology policy [PDF]
National science and technology policy is concerned with societal choices with respect to the rate and directions of technological change and the adoption and use of new technology in society.
Dunn, D. A.
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
GLOBALIZATION, CROPPING CHOICES, AND PROFITABILITY IN AMERICAN AGRICULTURE [PDF]
The paper discusses the linkages between the "globalization" of agricultural markets over recent decades and the decisions being made by individual farmers and ranchers in the United States.
Blank, Steven C.
core +1 more source
Extending systems-on-chip to the third dimension : performance, cost and technological tradeoffs. [PDF]
, 2007 Because of the today's market demand for high-performance, high-density portable hand-held applications, electronic system design technology has shifted the focus from 2-D planar SoC single-chip solutions to different alternative options as tiled silicon
Pamunuwa, Dinesh B. +3 more
core +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The Effect of Foreign Influence on Conflict and Social Identity in Ethnically Diverse Societies
GamesThis paper develops a formal model to analyze how foreign interventions—via resource transfers towards mobilization, technological upgrades of the mobilization technology, and various forms of conditional aid—reshape identity choices and conflict ...
Esther Hauk
doaj +1 more source