Results 121 to 130 of about 526,015 (308)

A Theory of Colonial Governance [PDF]

open access: yes
This paper considers conditions of optimality in a co-optive strategy of colonial rule. It proposes a simple model of elite formation emanating from a coloniser's quest to maximise extracted rents from its colonies.
J. W. Fedderke, J.A. Agbor, N. Viegi
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Technological innovation, R&D, FDI, and governance as drivers of economic growth: evidence from West African countries

open access: yesCogent Economics & Finance
This study investigates the effects of technological innovation (measured by patent applications), research and development (R&D), foreign direct investment (FDI), and governance on GDP per capita growth in 15 West African (ECOWAS) countries over 1991 ...
Raphael Ampedu   +6 more
doaj   +1 more source

People centred eco-design: consumer adoption of low and zero carbon products and systems [PDF]

open access: yes, 2007
Literature review, research model and findings of exploratory empirical research on consumer adoption and effective use of low and zero carbon technologies ranging from a hybrid car to solar water heating ...
Caird, Sally   +2 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The Connotation, Implementation, and Reflection of Ethics Primacy in the Governance of Medical Science and Technology Ethics

open access: yesYixue yu zhexue
The ethical governance of medical science and technology (MST) entails distinct characteristics. The principle of "ethics primacy" in MST governance implies, on one hand, that ethical considerations must not lag behind scientific and technological ...
Yongfu CAO
doaj   +1 more source

Global Governance of the Technological Revolution [PDF]

open access: yes, 2008
This paper discusses governance challenges of technologies emerging from the information technology (IT) and biotechnology revolutions. Of particular interest here are electronic communication and intelligent computing environments, emerging from the information revolution, and human genetic manipulation and bioinformatics, emerging from the ...
openaire   +2 more sources

Is there a Vicious circle in Muslim World? Trade competitiveness and investment strategies [PDF]

open access: yes
The study tests the existence of a vicious circle of the lack of investable funds, weaker technological advancement and business competitiveness in Muslim countries.
Mehar, Ayub
core   +1 more source

Evolution of Threats in the Global Risk Network

open access: yes, 2018
With a steadily growing population and rapid advancements in technology, the global economy is increasing in size and complexity. This growth exacerbates global vulnerabilities and may lead to unforeseen consequences such as global pandemics fueled by ...
Korniss, Gyorgy   +3 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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