Results 71 to 80 of about 303,086 (310)

The Undergraduate Scientific and Technological Innovation and Entrepreneurship Education Platform

MATEC Web of Conferences, 2016
Along with the development of innovation and entrepreneurship nowadays, how to promote the undergraduate scientific and technological innovation and entrepreneurship during the period of university education is more and more discussed by the people.
Song Jin Bao
doaj   +1 more source

The Effect of Technological Innovation on International Trade. A Nonlinear Approach [Dataset]

, 2010
In this paper, the effect of technological innovation on sectoral exports is analysed using a gravity model of trade. The technological achievement index (TAI) and its four components, creation of technology, diffusion of old innovations, diffusion of ...
Laura Márquez-Ramos, Inmaculada Martínez-Zarzoso   +1 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Technological Opportunities, Absorptive Capacities, and Innovation [PDF]

The aim of this paper is to analyze the effects of technological opportunities on the innovation activities of firms, depending on their absorptive capacities.
Wolfgang Becker, Juergen Peters
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Calculation and analysis of the efficiency of resource allocation for technological innovation in China.

PLoS ONE
The efficiency of resource allocation in technological innovation is a critical factor influencing the output level of technological innovation. By expanding and optimizing the Hsieh & Klenow (2009) framework for analyzing the efficiency of resource ...
Ruying Chen, Lanyu Wu
doaj   +1 more source

Innovative Instructional Technologies.

J. Univers. Comput. Sci., 2013
Innovative Instructional ...
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

How Large Are the Welfare Gains from Technological Innovation Induced by Environmental Policies? [PDF]

This paper examines whether the welfare gains from technological innovation that reduces future abatement costs are larger or smaller than the “Pigouvian” welfare gains from optimal pollution control.
Fischer, Carolyn, Parry, Ian, Pizer, William   +2 more
core   +2 more sources

Examining the relationship between technological innovation, environmental social governance and corporate sustainability: the moderating role of green operational innovation

Humanities & Social Sciences Communications
While environmental social governance (ESG) and technological innovation are important foundations for corporate sustainability, how ESG activities and technological innovation impact corporate sustainability remains limited in the current literature ...
Oluwole Nurudeen Omonijo, Yunsheng Zhang
doaj   +1 more source