Results 91 to 100 of about 2,995,711 (354)
The Evolution of Stop-motion Animation Technique Through 120 Years of Technological Innovations [PDF]
, 2018 Stop-motion animation history has been put on paper by several scholars and practitioners who tried to organize 120 years of technological innovations and material experiments dealing with a huge literature.
Maselli, Vincenzo
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Technological innovations and social development in Asia
Journal of Asian Public Policy, 2018 It is increasingly a concern that technological innovations may create as many problems as they solve. Together with the articles in this special issue, we outline the challenges and opportunities posed by technological changes to social development and ...
Bingqin Li, D. Piachaud
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
ADOPTION OF TECHNOLOGICAL INNOVATIONS BY SPORTS SPECTATORS [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2023 In the paper "Adoption of technological innovations by sports spectators" we make a brief analysis of the importance of technology in sports and in the fans' experience, and in the last part a technology used by both athletes and fans is presented ...
POPESCU MARIUS CĂTĂLIN +4 more
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
The impact of innovation on employment in Europe: An analysis using CIS data [PDF]
Technological progress in western economies has contributed to an immense rise in productivity, incomes and goods available over the last hundred years. Though not to the same extent as productivity and wages, population and employment have risen as well.
Blechinger, Doris +3 more
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Technological innovations and aggregate risk premiums [PDF]
, 2009 In this paper, I propose that technological innovations increase expected stock returns and premiums at the aggregate level. I use aggregate patent data and research and development (R&D) data to measure technological innovations in the U.S., and find ...
Hsu, PH
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