Results 41 to 50 of about 47,818 (311)

Discursive leadership in technological change [PDF]

open access: yes, 2016
Phd ThesisThis thesis is contributing to a greater understanding of discursive leadership by exploring as it happens in situ and by looking more closely at the daily interactional work of leadership actors in the process of technological change. In this
Gadelshina, Gyuzel
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Renewable Energy Transition: A New Geopolitical Game

open access: yesPerspective Politice
The global transition to renewable energy is not simply a shift toward a sustainable future, but a fundamental geopolitical reconfiguration. This article analyzes how this transition, while promising a decentralized energy landscape, is paradoxically ...
Vittorio AMATO
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

TECHNOLOGICAL LEADERSHIP AND ICT LITERACY AS KEYS TO INCREASING INNOVATIVE TEACHER BEHAVIOR

open access: yesJurnal Eduscience
Purpose-Technological leadership and ICT literacy are important factors in improving teachers' innovative behavior. This study is essential, considering the rapid development of information technology that requires teachers to innovate.
Dasmo Dasmo   +2 more
doaj   +1 more source

Legal support for technological policy in Russia: Systemic analysis and ways of improvement [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Серия «Экономика. Управление. Право»
Introduction. The implementation of the updated political course aimed at ensuring technological leadership requires comprehensive legal determination and creation of a balanced regulatory framework. Theoretical аnalysis.
Ilyukhina, Yulia Yurievna
doaj   +1 more source

Leadership and Information Technology

open access: yesNitte Management Review, 2016
The ubiquitousness of Information Technology requires that leaders of organizations in almost all industries have a good deal of knowledge of what Information Technology (IT) can do for their organizations. In every industry IT is making its presence felt in a big way. For organizational leaders the knowledge of how IT is impacting the industry and, in
K. Sankaran, Moshin Ahmed
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Developing leadership that matters: Transformational leadership

open access: yes, 2023
Highlights of this Working Paper Brief • Defines Transformational Leadership (TL). • Presents research on the positive effects of TL.
Chua, Paul Meng Huat   +1 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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