Results 91 to 100 of about 2,483,724 (310)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The impact of M&A on the R&D process. An empirical analysis of the role of technological and market relatedness. [PDF]

open access: yes
While the impact of M&A on R&D and innovation examined at the aggregate level left inconclusive evidence, we find that at the level of the R&D process both the technological and market relatedness between the target and acquirer are helpful dimensions to
Cassiman, B   +3 more
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

CoastalWQL: An Open-Source Tool for Drone-Based Mapping of Coastal Turbidity Using Push Broom Hyperspectral Imagery

open access: yesRemote Sensing
Uncrewed-Aerial Vehicles (UAVs) and hyperspectral sensors are emerging as effective alternatives for monitoring water quality on-demand. However, image mosaicking for largely featureless coastal water surfaces or open seas has shown to be challenging ...
Hui Ying Pak   +4 more
doaj   +1 more source

Control of technological process using PLC [PDF]

open access: yes, 2012
Ve své práci se zabývám rozborem programovatelných automatů simatic, má práce zahrnuje tyto prvky: Historie PLC; programovatelný automat, jehorozdělení a funkce, programovací jazyky, programovací prostředí STEP, komunikace s PLCMy work deals with ...
Pavela, Martin
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties. [PDF]

open access: yesMaterials (Basel), 2021
Gębarowski T   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Side-polished fiber evanescent wave quartz-enhanced photoacoustic spectroscopy employing dielectric coatings for evanescent field enhancement

open access: yesPhotoacoustics
We report an all-fiber laser gas analyzer (LGA) based on quartz-enhanced photoacoustic spectroscopy (QEPAS) that exploits strong evanescent wave (EW) enhancement using a dielectric coating on side-polished fiber.
Cian F. Twomey   +6 more
doaj   +1 more source

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