Results 101 to 110 of about 2,483,724 (310)

A Peer-to-Peer Architecture for Distributed Knowledge Management. [PDF]

open access: yes, 2002
Most of the knowledge management systems of complex organizations are based on technological architectures that are in contradiction with the social processes of knowledge creation. In particular, centralized architectures are adopted to manage a process
Bonifacio, Matteo   +3 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

SPILLOVERS IN PRODUCT AND PROCESS INNOVATION: EVIDENCE FROM MANUFACTURING FIRMS [PDF]

open access: yes
This paper proposes a new empirical approach to assess the impact of knowledge spillovers on firms' productivity and demand. I consider a model where process innovations spillovers to other firms raise firms relative efficiency and technological ...
Carmine Ornaghi
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Cascaded Directional Coupler-Based Triplexer Working on Spectroscopically Relevant Wavelengths for Multiple Gas Detection

open access: yesPhotonics
In this article, we present experimental and simulation results of a novel high-performance cascaded directional coupler-based triplexer. The device is designed to combine the wavelengths of 1530 nm, 1653.7 nm, and 2003 nm for use in spectroscopy systems
Ajmal Thottoli   +5 more
doaj   +1 more source

Technological Backwardness in Agriculture: Is It due to Lack of R&D Expenditures, Human Capital and Openness to International Trade? [PDF]

open access: yes
In this paper we investigate the relationship between the agricultural technological level and R&D expenditures, human capital and openness to international trade using cross country information for a sample of 104 countries and various sub samples over ...
Rodolfo Cermeño, Sirenia Várquez
core  

Technological learning: towards an integrated model [PDF]

open access: yes, 2001
The acquisition and growth of technological knowledge is fundamental to competitive advantage in the emerging knowledge economy. This article explores the notion of technological learning as a means of developing the capabilities that underpin long term ...
Byrne, S.   +3 more
core  

Home - About - Disclaimer - Privacy