Results 91 to 100 of about 658,493 (351)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

RUSSIAN EXPERIENCE IN ENGINEERING EDUCATION DEVELOPMENT

Высшее образование в России, 2018
The implementation of the large-scale system program devoted to the development of a new technological generation economy announced by the President of Russia V.V. Putin in his Address to the Federal Assembly of the Russian Federation on December 1, 2016
A. I. RUDSKOY, A. I. BOROVKOV, P. I. ROMANOV   +2 more
doaj  

Evaluation of Geohazards Research in the World and Pacific Region: A Comparative Bibliometric Study

Iraqi Geological Journal
Geohazards are natural phenomena that endanger infrastructure, the environment, and human activity. Understanding and mitigating them is crucial for public safety, disaster preparedness, and sustainable land and resource management.
Khoirun Nisa, Nadi Suprapto, Iqbal Rizki
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Efficacy of Emerging Technologies to Manage Childhood Obesity

Diabetes, Metabolic Syndrome and Obesity, 2022
Mohammad Alotaibi,1 Fady Alnajjar,2 Massimiliano Cappuccio,3 Sumaya Khalid,2 Tareq Alhmiedat,1,4 Omar Mubin5 1Faculty of Computers and Information Technology, University of Tabuk, Tabuk, Saudi Arabia; 2College of Information Technology, United Arab ...
Alotaibi M, Alnajjar F, Cappuccio M, Khalid S, Alhmiedat T, Mubin O   +5 more
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Innovative aspects of underground coal gasification technology in mine conditions [PDF]

, 2018
Purpose. Development of innovative approaches in technological and technical solutions improvement for coal seam gasification. Methods. Carrying-out of native and world experience in the coal reserves development by underground gasification technology ...
Dychkovskyi, R, Falshtynskyi, V, Lozynskyi, V, Petlovanyi, M, Saik, P   +4 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Nanomedicine applications in orthopedic medicine: state of the art

International Journal of Nanomedicine, 2015
Mozhdeh Mazaheri,1,* Niloofar Eslahi,1,* Farideh Ordikhani,1,* Elnaz Tamjid,2 Abdolreza Simchi1,3 1Department of Materials Science and Engineering, Sharif University of Technology, 2Department of Nanobiotechnology, Faculty of Biological Sciences ...
Mazaheri M, Eslahi N, Ordikhani F, Tamjid E, Simchi A   +4 more
doaj  

Scientific culture from the University. Research competence evaluation of students enrolled in the Summer Science Programs

Education in the Knowledge Society, 2017
The training of young researchers from tertiary education represents a latent concern in educational centers worldwide. In that sense, there are private and public initiatives that encourage scientific culture inside and outside the school curriculum ...
Abel Antonio GRIJALVA VERDUGO, María Luisa Urrea ZAZUETA   +1 more
doaj   +1 more source