Results 111 to 120 of about 80,011 (312)
IEEE AccessLaser Powder Bed Fusion (LPBF) is a crucial additive manufacturing technique that builds complex geometries by selectively melting metal powders. However, it faces challenges from defects such as ditches, stacking, insufficient spreading, and craters ...
Zihan Yang +8 more
doaj +1 more source
Modeling Endogenous Technological Change for Climate Policy Analysis [PDF]
The approach used to model technological change in a climate policy model is a critical determinant of its results. We provide an overview of the different approaches used in the literature, with an emphasis on recent developments regarding endogenous ...
Gillingham, Kenneth T. +2 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2019 Teachers are probably the most important factor in the educational process because of their role in organising students’ learning experiences. Future teachers require high levels of information, knowledge and skills to enable them to perform successfully
Al-Tukruni, Elham
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Single-cell laser emitting cytometry for label-free nucleolus fingerprinting
Nature CommunicationsThe nucleolus, a recognized biomolecular condensate, serves as the hub for ribosome biogenesis within the cell nucleus. Its quantity and morphology are discernible indicators of cellular functional states.
Guocheng Fang +9 more
doaj +1 more source
On the design of design processes in architecture and engineering: technological rules and the principle of minimal specification [PDF]
architecture, design process ...
Aken van, J.E.
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Energy technology for climate change: accelerating the technology response
, 2009 The key finding of this report by the Australian Academy of Technological Sciences and Engineering (ATSE) is that a commitment is needed by government and industry to invest around $6 billion by 2020 on RD&D on new power generation technologies ...
John Burgess
core
A bridge between conceptual frameworks: sciences, society and technology studies
, 2015 This book analyzes scientific problems within the history of physics, engineering, chemistry, astronomy and medicine, correlated with technological applications in the social context. When and how is tension between disciplines explicitly practised? What
Pisano, Raffaele
core +1 more source