Results 91 to 100 of about 80,011 (312)

In Defense of Engineering Sciences: On the Epistemological Relations between Science and Technology [PDF]

, 2011
This article presents an overview of discussions in the philosophy of technology on epistemological relations between science and technology, illustrating that often several mutually entangled issues are at stake.
Boon, Mieke; id_orcid, Boon, Mieke
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The relevance of technology in the organisation of work in a third world workplace: A case study of the Port Harcourt refinery, Nigeria

, 1993
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The organisation of work is seen here as concerning the ways in which various elements in work such as skills, tasks and structures of relationship are ...
Nwuche, C.A, Nwuche, Christine Adaobi
core  

Collaborative Reverse Engineering Design Experiment Using PLM Solutions [PDF]

, 2011
The current climate of economic competition forces businesses to adapt to the expectations of their customers. To achieve this, in spite of the increasing complexity of mechanical systems, it becomes necessary, amongst other things, to reduce design time.
AOUSSAT, Améziane, VERON, Philippe, SEGONDS, Frederic, MARANZANA, Nicolas   +3 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Smart connected farms and networked farmers to improve crop production, sustainability and profitability

Frontiers in Agronomy
To meet the grand challenges of agricultural production including climate change impacts on crop production, a tight integration of social science, technology and agriculture experts including farmers are needed.
Asheesh K. Singh, Behzad J. Balabaygloo, Barituka Bekee, Samuel W. Blair, Suzanne Fey, Fateme Fotouhi, Ashish Gupta, Amit Jha, Jorge C. Martinez-Palomares, Kevin Menke, Aaron Prestholt, Vishesh K. Tanwar, Xu Tao, Anusha Vangala, Matthew E. Carroll, Sajal K. Das, Guilherme DePaula, Peter Kyveryga, Soumik Sarkar, Michelle Segovia, Simone Silvestri, Corinne Valdivia   +21 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Dissonance in the Algorithmic Era: Evaluating Showcase Digital Competence and Ethical Resilience in Communication Training

Journalism and Media
The disruptive acceleration of Generative Artificial Intelligence (GAI) has amplified the phenomenon of Global Friction (Globofriction), where technological speed undermines informational stability and weakens democratic resilience.
Esma Kucukalic Ibrahimovic
doaj   +1 more source

Technological breakthroughs and asset replacement [PDF]

The authors analyze the optimal replacement of assets under continuous and discontinuous technological change. They investigate the variable lifetime of assets in an infinite-horizon replacement problem.
Yatsenko, Yuri, Hritonenko, Natali
core  

Drinking water through recycling: the benefits and costs of supplying direct to the distribution system [PDF]

, 2013
This report argues that returning highly treated wastewater directly into Australia\u27s drinking water supply could have considerable economic and environmental benefits.
Khan, Stuart, Stuart Khan
core