Results 51 to 60 of about 89,198 (230)
Digital architecture and its impact on architectural engineering education
Journal of Architecture, Art & Humanistic Science, 2019 In fact, the world is witnessing daily discoveries and developments in modern computer, communications and technology, the result turned into the industries, and then emerged new scientific concepts, which led to a radical change in these sciences or the
Shimaa Ibrahim
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A practice based learning environment for engineering students: Acquiring competencies for working on advanced manufacturing engineering [PDF]
, 1995 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In this thesis the author describes the design and operation of a learning environment aimed at imparting technical, technological and managerial knowledge,
Schmid, Felix
core +6 more sources
Three-round learning strategy based on 3D deep convolutional GANs for Alzheimer’s disease staging
Scientific Reports, 2023 Accurately diagnosing of Alzheimer's disease (AD) and its early stages is critical for prompt treatment or potential intervention to delay the the disease’s progression.
Wenjie Kang +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Contextualization of basic sciences in technological degrees [PDF]
, 2020 This Research-to-Practice Work in Progress paper presents a project based on increasing the motivation and performance of undergraduate technology students.
Peña Carrera, Marta +1 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Nature Communications, 2022 Improving piezoelectric strain and voltage constant generally compromises piezoelectric performance and mechanical softness. Here, the authors report a bond weakening strategy for organic-inorganic hybrid piezoelectrics and mitigated these issues.
Yuzhong Hu +18 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source