Results 61 to 70 of about 653,731 (310)

Digital architecture and its impact on architectural engineering education

open access: yesJournal of Architecture, Art & Humanistic Science, 2019
In fact, the world is witnessing daily discoveries and developments in modern computer, communications and technology, the result turned into the industries, and then emerged new scientific concepts, which led to a radical change in these sciences or the
Shimaa Ibrahim
doaj   +1 more source

DATUM in Action [PDF]

open access: yes, 2012
This collaborative research data management planning project (hereafter the RDMP project) sought to help a collaborative group of researchers working on an EU FP7 staff exchange project (hereafter the EU project) to define and implement good research ...
Childs, Sue, McLeod, Julie
core  

Alvin Weinberg and the promotion of the technological fix [PDF]

open access: yes, 2018
The term “technological fix”, coined by technologist/administrator Alvin Weinberg in 1965, vaunted engineering innovation as a generic tool for circumventing problems commonly conceived as social, political or cultural.
Johnston, Sean F.
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Safety and security management through an integrated multidisciplinary model and related integrated technological framework [PDF]

open access: yes, 2018
The purpose of this paper is to illustrate a multidisciplinary model for safety and security management (IMMSSM) which can be implemented by means of a suitable Integrated Technological System Framework (ITSF) that can be based on Internet of Things (IoT)
Garzia, Fabio, Lombardi, Mara
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Why social scientists should engage with natural scientists [PDF]

open access: yes, 2013
It has become part of the mantra of contemporary science policy that the resolution of besetting problems calls for the active engagement of a wide range of sciences.
Lowe, Philip   +2 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Bond engineering of molecular ferroelectrics renders soft and high-performance piezoelectric energy harvesting materials

open access: yesNature Communications, 2022
Improving piezoelectric strain and voltage constant generally compromises piezoelectric performance and mechanical softness. Here, the authors report a bond weakening strategy for organic-inorganic hybrid piezoelectrics and mitigated these issues.
Yuzhong Hu   +18 more
doaj   +1 more source

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