Results 61 to 70 of about 89,198 (230)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

RUSSIAN EXPERIENCE IN ENGINEERING EDUCATION DEVELOPMENT

Высшее образование в России, 2018
The implementation of the large-scale system program devoted to the development of a new technological generation economy announced by the President of Russia V.V. Putin in his Address to the Federal Assembly of the Russian Federation on December 1, 2016
A. I. RUDSKOY, A. I. BOROVKOV, P. I. ROMANOV   +2 more
doaj  

Efficacy of Emerging Technologies to Manage Childhood Obesity

Diabetes, Metabolic Syndrome and Obesity, 2022
Mohammad Alotaibi,1 Fady Alnajjar,2 Massimiliano Cappuccio,3 Sumaya Khalid,2 Tareq Alhmiedat,1,4 Omar Mubin5 1Faculty of Computers and Information Technology, University of Tabuk, Tabuk, Saudi Arabia; 2College of Information Technology, United Arab ...
Alotaibi M, Alnajjar F, Cappuccio M, Khalid S, Alhmiedat T, Mubin O   +5 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

A emancipação da tecnologia em relação à ciência [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Programa de Pós-Graduação em Filosofia, Florianópolis, 2014.O objetivo básico desta tese consiste em explorar a índole da ciência e da tecnologia e os ...
Szczepanik, Gilmar Evandro
core  

Evaluation of Geohazards Research in the World and Pacific Region: A Comparative Bibliometric Study

Iraqi Geological Journal
Geohazards are natural phenomena that endanger infrastructure, the environment, and human activity. Understanding and mitigating them is crucial for public safety, disaster preparedness, and sustainable land and resource management.
Khoirun Nisa, Nadi Suprapto, Iqbal Rizki
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Nanomedicine applications in orthopedic medicine: state of the art

International Journal of Nanomedicine, 2015
Mozhdeh Mazaheri,1,* Niloofar Eslahi,1,* Farideh Ordikhani,1,* Elnaz Tamjid,2 Abdolreza Simchi1,3 1Department of Materials Science and Engineering, Sharif University of Technology, 2Department of Nanobiotechnology, Faculty of Biological Sciences ...
Mazaheri M, Eslahi N, Ordikhani F, Tamjid E, Simchi A   +4 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source