Results 91 to 100 of about 152,989 (306)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Do Firms Benefit from Being Present in Multiple Technology Clusters? An Assessment of the Technological Performance of Biopharmaceutical Firms [PDF]
Firms active in knowledge-intensive fields are increasingly organizing their R&D activities on an international scale. This paper investigates whether firms active in biotechnology can improve their technological performance by developing R&D activities ...
Jeroen Kusters +3 more
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FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Influence of Technological and Structure Properties on Shape of Asymmetric Plywood Sheet
The paper presents a numerical study of the technological process and plywood structure (veneer arrangement and thickness) influence on shape of sheet.
Rocēns, Kārlis, Šliseris, Jānis
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, 1998 This thesis examines the theory of technological determinism, which espouses\ud the view that technological change drives social change, through an analysis of\ud the impact of new media on higher education models in the United States of\ud America.
Tapsall, Suellen Maree
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Energy efficiency and using less – a social sciences and humanities annotated bibliography [PDF]
, 2017 The challenge: * Technological progress and changes in energy supply are not sufficient for a transition to a low-carbon energy system; demand also needs to be considered.
Uitdenbogerd, Diana +38 more
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Empirical Musicology Review, 2013 This commentary responds to some of the debates and issues raised by Alinka Greasley and Helen Prior's paper on DJing and musical shape. In particular, I focus on the use of technology by DJs, and how shifts within this domain are redefining the concept ...
Ed Montano
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Global shape reconstruction of nano grid with singly fixed camera
, 2011 Depth from defocus (DFD), as a typical shape reconstruction method, has been widely researched in most recent years. However, all the existing DFD algorithms require at least two defocused images with different camera parameters.
Wei YJ(魏阳杰) +2 more
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