Results 71 to 80 of about 152,989 (306)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Shaping factors in the emergence of technological innovations: The case of tidal kite technology [PDF]
, 2018 The technological innovation systems (TIS) literature offers a detailed and dynamic understanding of factors that enable successful innovation. However, few studies analyze what determines where in space value chain elements are developed as a new ...
Andersson, Johnn +8 more
core +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
PLoS ONEAs the Fourth Industrial Revolution advances, technological innovation has emerged as a key driver for firms to shape core competitiveness. The corporate governance literature recognizes CEO personality traits as key determinants of a firm's ...
Yuanbo Hu +3 more
doaj +1 more source
The Shape of Global Technology Assessment
, 2023 AbstractThis chapter draws tentative conclusions from the findings of the book contributions with regard to possible future ways to organise TA on a global scale. These considerations comprise a discussion of possible organisational shapes that can support the global interchange and sharing of TA capacities, and increase its political relevance and ...
Miltos Ladikas +5 more
openaire +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An experimental investigation of shape memory polymer for alcohol activated self-tightening band-aid
, 2020 Band-aid in the form of Shape Memory Polymers has a great potential in revolutionising the way we can close our wound.Bachelor of Engineering (Mechanical ...
Chia, Benjamin Jia Xun
core
Литьë и металлургия, 2005 The results of adjustment of the technological process of casting of the cylinders block head ingots of cast iron with vermicular shape of graphite are presented.
A. N. Krutilin +6 more
doaj
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source