Results 91 to 100 of about 19,069,371 (303)
Charting new waters in higher education institutes: navigating the role of technological universities in Ireland and Europe [PDF]
The higher education sector in Ireland is described. Changes in that sector during the period from 1960 to the current time are outlined and discussed.
Griffin, James, Collins, James
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Trudy Odesskogo Politehničeskogo Universiteta, 2014 At elongated holes boring several imperfections can occur, namely, the surface waviness and shape inaccuracies in the axial section. This research purpose is to establish the regularities of such imperfections formation depending on the technological ...
Boris О. Tkachenko, Аnna V. Balaniuk
doaj +1 more source
A Technological System for Post-Earthquake Damage Scenarios Based on the Monitoring by Means of an Urban Seismic Network. [PDF]
Sensors (Basel), 2021 Costanzo A +7 more
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
大数据With the rapid development of big data, cloud computing, and artificial intelligence, data circulation security governance faces new challenges and requires a systematic and sustainable growth technology system.
CHEN Yucun, HUANG Keman, DU Xiaoyong
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Understanding the formative stage of Technological Innovation System development. The case of natural gas as an automotive fuel [PDF]
This study contributes to insights into mechanisms that influence the successes and failures of emerging energy technologies. It is assumed that for an emerging technology to fruitfully develop, it should be fostered by a Technological Innovation System (
Roald A.A. Suurs +3 more
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Technological Evolution and Critical Path Economics [PDF]
, 1998 Technological leadership positions may be threatened by significant shifts in product system performance requiring corresponding shifts in the leading firm's core competences.
Gottinger, Hans W.
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source