Results 151 to 160 of about 2,174,176 (234)

Explaining the Use Behavior of Digital Technologies in Pediatric Rehabilitation: Structural Equation Modeling Analysis of a Cross-Sectional European Survey. [PDF]

J Med Internet Res
Mensah Gourmel J, Brochard S, Bekteshi S, Monbaliu E, Cornec G, Grigoriu AI, Newman CJ, Konings M, De La Cruz J, Pons C.   +9 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Understanding the value of virtual care technologies: development of a framework in the veterans health administration. [PDF]

Front Digit Health
Hogan TP, Etingen B, McMahon N, Escudero G, Calkins S, Moussa A, Slightam C, Zulman D, Shimada SL, Robinson SA, Zocchi MS, Shah N, Heyworth L, Newton TJ.   +13 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Correction: Molecular subtypes and the (in vitro) response of glioblastoma to temozolomide. [PDF]

BJC Rep
Rancati S, Campolungo M, Duarte Dalmolin G, Lau P, Furia F, Coppe A, Landuzzi F, Vecchi M, Cavalli A, Gustincich S, Tirelli N.   +10 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The evolution of display technologies for antibody drug discovery. [PDF]

Trends Biotechnol
Rojo-Gallegos J, Tang JQ, Yarmarkovich M, DeKosky BJ.   +3 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Editorial: Incorporating non-thermal technologies to enhance food fortification strategies: current trends and future directions in personalized nutrition. [PDF]

Front Nutr
Nasiru MM, Muhammad AI, Boateng EF.
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source