Results 221 to 230 of about 7,420,775 (255)

Pilot and testbed facilities: when the lab scale may not be enough. [PDF]

Commun Eng
Huusom JK, Junicke H, Morgan J, Searle J, Blagoeva D, Malkow T, Pitois A, Pfrang A.   +7 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Artificial Intelligence for Microbial Isolation and Cultivation: Progress and Challenges. [PDF]

Microorganisms
Li M, Yao X, Zhang M, Hu B.
europepmc   +1 more source

Emerging technologies for learning (volume 2) [PDF]

, 2007
Bryant, Lee, Downes, Stephen, Dumbleton, Tim, Facer, Keri, Ley, David, Prensky, Marc, Twist, Jo   +6 more
core  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Public Knowledge and Acceptance of Artificial Intelligence-Assisted Physicians in Saudi Arabia: A Cross-Sectional Study. [PDF]

Int J Gen Med
Alhindi Y, Almoqati H, Alsaadi R, Alabbas LM, Alhuzali M, Alamoudi R, Khawaji H, Alharbi AA, Fallatah A, Muharrij A, Alluhaybi MB, Alotaibi WS, Alahmadi B, Alqurashi N, Fairaq A.   +14 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Digital Futures in an Ageing Society: Frontline Perspectives on Sociotechnical Imaginaries in Swedish Eldercare. [PDF]

Sociol Health Illn
Morris F, Thelandersson F, Sandberg H.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Smart Packaging 4.0: A Bibliometric Analysis of Sensor Integration, Food Safety, and Sustainability in Food Packaging Systems. [PDF]

ScientificWorldJournal
Djafar MJ, Elmatsani HM, Munarso SJ, Firdaus J, Trihadi SEY, Purwanta W, Sadikin BS, Sahlan S, Nasruddin N, Lanjar L.   +9 more
europepmc   +1 more source